Authors say findings show importance of preventing chronic conditions earlier in life versus later in life

Additionally, the frequency of diabetic ketoacidosis at presentation increased

Lower insulin area under the curve and higher glucose area under the curve observed with late dinner timing

Observational and genetically predicted links seen between indices of obesity and female reproductive disorders

Faricimab noninferior to aflibercept for visual acuity gains in neovascular age-related macular degeneration, diabetic macular edema

Significantly lower rates of initiation seen in Black and American Indian or Alaskan Native individuals

All-cause inpatient admissions 2.8 times more likely, death 1.5 times more likely during foot ulcer episodes versus period after healing

Stronger association seen for moderate- to vigorous-intensity steps per day than for light-intensity steps per day

However, some small but significant increases and decreases seen in specific geographic areas

No similar findings seen for middle-aged women