Accompanying editorial indicates no evidence of an adverse effect at lower water fluoride levels commonly used in water systems

Clinical practice guideline also presents recommendations for specialist care and primary care of patients with Alzheimer disease, dementia

However, no association seen between NSAID use and fetal nephrotoxicity in sibling comparisons

Decrease consistent with decreasing use of screening mammography since 2009 guideline change

Findings consistent across degrees of missing teeth in dentate participants

No significant difference seen in composite of 30-day mortality or MI; cardiac death at 30 days increased with restrictive strategy

Approval based on noninferior pharmacokinetic exposures, similar effectiveness and safety to intravenous Opdivo

When comparing assessments of lymph nodes, tonsils, total Centor score, agreement was low, with kappa between 0.47 and 0.58

Increase in odds of dementia diagnosis seen with age among those with ASD only and ASD plus intellectual disabilities

Benefits include better discrimination between risk levels