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In a retrospective study, gastric banding was found to help resolve or improve comorbidities like asthma, HTN, sleep apnea, and GERD; significantly improved glucose metabolism, caused cessation or reduction in oral hypo-glycemics and insulin; and improved glycemic control, insulin sensitivity, and beta-cell function. Gastric banding completely resolved type 2 diabetes …

FDA Approves Repaglinide (Generic Prandin)  FDA gives final approval for the generic form of Novo’s Prandin (repaglinide) to Sun Pharmaceutical Industries.

Data on Alzheimer’s disease patients revealed 30% had glucose intolerance and 13% showed results consistent with diabetes two hours after a first fasting glucose tolerance test. This suggests that undiagnosed prediabetes and diabetes are common among patients with Alzheimer’s disease, and that these patients should be subject to screening, a …

About 35.1% of diabetes patients who attained remission following gastric bypass surgery redeveloped the disease within five years, according to a study. Longer diabetes duration, insulin use and poor preoperative glycemic control were associated with a higher risk of diabetes relapse, researchers said. Obesity Surgery 2013 

 Researchers studied the growth factor family that negatively regulates skeletal muscle growth and myostatin (MSTN). They found that overexpression of the myostatin (MSTN) gene resulted in elevated insulin resistance and obesity. In contrast, MSTN gene deletion increased the muscle mass in mice models, reduced resistance to diet-induced obesity, and increased …

Roche stops diabetes drug development following safety concerns. Roche Holding announced it will cease the development of its diabetes drug aleglitazar after a late-stage trial revealed the medication negatively affects the kidneys and the heart.

Randomized, controlled phase III clinical data demonstrate buccal insulin’s effectiveness and non-inferiority when compared to injected human insulin. The study was conducted at 14 sites in India with 209 type 2 patients between 18 and 75 years of age with at least one year of use of oral anti-diabetes medications; …

Thomas P. J. Solomon, PhD, of the Centre of Inflammation and Metabolism, Copenhagen, and colleagues studied body composition, aerobic fitness and glycemic control in 105 overweight or obese patients (mean BMI, 33 kg/m2; mean age, 61 years) with impaired glucose tolerance (n=56) or type 2 diabetes (n=49) before and after …

The UN Food and Agriculture Organization reports that 32.8% of Mexican adults are obese, compared with 31.8% of adults in the U.S. Diabetes kills as many as 70,000 people a year in Mexico — roughly equal to the deaths authorities say are caused by more than six years of the …

Crucial Rule Is Delayed a Year for Affordable Care Act  The administration has announced a delay in the mandate that larger employers cover their workers, postponing the effective date beyond next year’s midterm elections. See this week’s Item #1.