FDA Approves Once-Weekly Dulaglutide for Type 2 Diabetes Once-weekly dulaglutide was approved based on six clinical trials involving a total of 3,342 patients who received the drug. It was studied as a stand-alone therapy and in combination with metformin, sulfonylurea, thiazolidinedione, and prandial insulin.
Read More »Saccharin May Impair Glucose Metabolism
Researchers from the Weizmann Institute of Science in Israel found that differences in gut microbes may explain why some people can handle artificial sweeteners just fine while in others the sweeteners lead to glucose intolerance. In studies in mice and people, researchers examined the interaction between gut microbes and consumption …
Read More »The Staggering Cost of Diabetes
According to the ADA, total annual costs associated with diagnosed diabetes cases increased by 41% between 2007 and 2012, and the total estimated cost for care of those in the U.S. with diagnosed diabetes in 2012 was $245 billion. People diagnosed with diabetes spend about $13,700 per year on medical …
Read More »Empagliflozin/linagliptin Combo Tablet Shows Sustained Reduction in BG
Boehringer Ingelheim, and Eli Lilly & Co. have presented results from a 52-week Phase III study demonstrating sustained efficacy of the investigational empagliflozin/linagliptin combination tablet in adults with T2DM already taking metformin and in those who were previously untreated. The results, presented during the 50th Annual Meeting of the European …
Read More »FDA Approves Weight Loss Drug Contrave
FDA Approves Weight Loss Drug Contrave. See this week’s Item #4. FDA Advisory Panel Recommends Approval of Novo Nordisk’s liraglutide (used now as Victoza to treat type 2 diabetes ) for use in chronically obese patients with at least one weight-related health issue. More news to come. The new drug would be …
Read More »Prediabetes and Obesity Tied to Overall Increased Risk for Cancer
"Lifestyle intervention (weight control, stop smoking and healthy diet, etc.) should be suggested earlier and recommended as the mainstay of treatment for prediabetes in the general population," said researcher Dr. Yuli Huang, who also said data on the effects of treatment with metformin are needed. See this week’s Item #1.
Read More »Cardiac Protein May Contribute to Higher Heart Risk in Diabetes
A study found diabetes patients were more than twice as likely as people without the disease to exhibit elevated troponin levels. Researchers also found diabetes patients had a six fold increased odds of dying from heart failure and were four times as likely to die of a heart attack during …
Read More »Statins Can Protect against Diabetes-related Nerve, Retina Damage
Diabetes patients who took statins had lower odds of developing diabetes-related nerve and retinal damage compared with nonusers, according to a study of data involving more than 60,000 patients in Denmark. Statin use was also associated with reduced risk of gangrene. The Lancet Diabetes & Endocrinology. Sept. 9, 2014
Read More »Poll Finds “Added Sugars” Label Confuses People
There is a debate over the FDA’s new Nutrition Facts label design, which requires "sugars" and "added sugars" to be listed separately. A Kellogg online survey showed that 22% of consumers incorrectly identified the amount of sugar in a product because they were adding the two sugar numbers together. The …
Read More »Skipping Breakfast Increases Diabetes Risk
British researchers found children who skipped breakfast had 24.4% higher fasting insulin and 26.7% higher insulin resistance compared with those who regularly ate breakfast. Children who ate breakfast daily, particularly a high fiber, cereal breakfast, had a more favorable type 2 diabetes risk profile. PLOS Medicine
Read More »
Diabetes In Control. A free weekly diabetes newsletter for Medical Professionals. News and information for Medical Professionals.