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Letter from the Editor
A lot of people will tell you that I am a gadget guy, and sometimes I just have to have something before everyone has even heard about it. As an example I am the proud owner of a Twicycle, a road bike that you can pedal with both your hands and your feet. One of the gadgets I bought about 3 years ago was a whole-body vibration device. I had read a couple of articles on the benefits of improved strength and endurance. As with most other new devices I got, I shared my enthusiasm with others and they all thought I was crazy.
This week in our special “Did You Know” series we have an article from the International Journal of Molecular Sciences, showcasing how these WBV devices can improve your health, as well as reduce insulin resistance and lessen the symptoms of diabetes.
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We can make a difference!
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Dave Joffe
Editor-in-chief
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Did You Know: Shake, Rattle and Vibrate -- Whole-body Vibrations Improve Diabetes Complications
A new study reveals the beneficial effects of whole-body vibration (WBV) on inflammation and the microbiome. WBV is a form of passive exercise that first appeared in the late 1990s and gained popularity in the last decade as a form of fitness training. WBV requires a person to stand on a platform that typically vibrates at a frequency of 15–70 hertz (Hz) and an amplitude of 1–10 millimeters (mm). The current dietary pattern, coupled with massively reduced physical activities, causes an epidemic of obesity and chronic metabolic diseases, such as type 2 diabetes mellitus. Chronic inflammation is a major contributing factor to the initiation and progression of most metabolic and cardiovascular diseases. Among all components of an innate immune system, due to their dual roles as phagocytic as well as antigen-presenting cells, macrophages play an important role in the regulation of inflammatory responses, affecting the body’s microenvironment and homeostasis. Earlier studies have established the beneficial, anti-inflammatory effects of WBV as a partial exercise mimetic, including reversing the effects of glucose intolerance and hepatic steatosis. Here for the first time, the mechanisms are described by which WBV may improve metabolic status and ameliorate the adverse consequences through macrophage polarization and altering the fecal microbiome. The human body automatically adapts to “repeated, rapid, and short intermittent exposure to oscillations” from this type of vibrating platform, which prompted researchers to classify WBV as a “light neuromuscular resistance training method.” Research into the practice has brought to light various health benefits. Some studies have shown that WBV improves muscle performance, bone density, strength, and balance, as well as helping to reduce body fat in the long term. Importantly, previous research has also shown that WBV can reduce inflammation and even “reverse many symptoms” of type 2 diabetes, such as frequent urination and excessive thirst. Research indicates that it also improves blood sugar control and insulin resistance, as measured by the standard glucose tolerance test and the hemoglobin A1C blood sugar test. This study set out to investigate how WBV can exert these benefits. International Journal of Molecular Sciences
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Nadeen Ayad, PharmD.Candidate
Kassey James, Pharm.D. Candidate, LECOM School of Pharmacy
Onyi Ibeji, PharmD. Candidate, LECOM School of Pharmacy
Amber Satz, PharmD Candidate, LECOM School of Pharmacy
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