July 14, 2018 : Issue #946

American Diabetes Association 78th Scientific Sessions Special Issue
This newsletter is Part 3 of our series on all the breaking news coming from the 78th Scientific Sessions of the American Diabetes Association 2018 in Orlando

• Poster Summaries of Interest at the 78th ADA Scientific Sessions
• Abstracts of Interest at the 78th ADA Scientific Sessions
• ADA: CGM Comparisons — Advances, Pitfalls, and Clinical Relevance
• ADA: Closed-Loop Insulin Delivery Improves Glycemic Management in Patients Who Are Hospitalized
• ADA: A Vaccine Can Improve Blood Glucose Management
• Can a Single Blood Sample Sufficiently Diagnose Diabetes?

Sometimes it is more important how you say something than what you are trying to say. For example, if you tell someone, “You have a face that would stop a clock,” you will likely get a slap in the face or a look of scorn, but if you say, “You have a face that makes the hands of time stand still,” you will likely get a smile and almost certainly a thank you.

These two messages say the same thing, but the way they were said makes all the difference in the world. The way we say things to our patients can be interpreted many different ways, and this week we are happy to have as our Tool for Practice, the new AADE Power of Language tool. This tool was inspired by two of our board members, Jane K. Dickinson RN, PhD, CDE, and Susan J. Guzman, PhD.

Also this week in our continuing ADA Scientific Coverage, we had our Doctor of Pharmacy Interns review some of the best Posters and Abstracts. With over 350 to choose from, it was a hard choice, but they were able to narrow it down for you. The cool thing about these items is that what you read today will likely be part of your standards of care in the future.

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We can make a difference!

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Dave Joffe

Editor-in-chief

At what A1c do you feel comfortable using triple therapy for a patient with type 2 and excessive weight? 8%, 9%, 10%, or 11%?

Follow the link to respond.

The FDA is strengthening the current warnings in the prescribing information for fluoroquinolone antibiotics due to the potential for significant decreases in blood sugar and certain mental health side effects. — FDA MedWatch

More than 30 million people have diabetes and one in three U.S. adults has prediabetes. It is therefore highly likely that during your career, you will discuss or write about diabetes. From the AADE comes guidance on how to talk and write about people with diabetes. Learn why it’s better to writer or say “person with diabetes” instead of using “diabetic.” Or, why it makes sense to use words such as “participation” or “involvement” instead of “compliance” or “adherence.” Jane K. Dickinson RN, PhD, CDE, and Susan J. Guzman, PhD, board members of Diabetes In Control, are co-authors on the joint language paper published by AADE and ADA in 2017 that was the inspiration for this media guide.

Download PDF: The Power of Language

Mr. Huang is a 61-year-old Asian American businessman who comes in to see you for a follow-up appointment. He was diagnosed with type 2 diabetes four years ago and has a long-standing history (15 years) of hypertension and hypercholesterolemia, which are currently well-controlled. Current medications are metformin (1500 mg/day), lisinopril, and simvastatin. He has excess weight (BMI 29 kg/m2) but feels he has a healthy diet and gets out for a 25-30 minute walk 3 or 4 times per week. He feels great, but over the last nine months or so, he has noticed that his home average glucose levels are in the 180-198 mg/dL range. At today’s visit, his A1C is 8.3%.

Based on Mr. Huang’s individual glycemic target of A1C<7%, you would like to add another antihyperglycemic. You choose linagliptin over glimepiride. What is the best reason for your choice? A. Greater weight loss benefits
B. More effective at lowering blood glucose levels
C. Lower cost of treatment

Follow the link for the answer.

Yanping Li et al report in Circulation that never smoking, having a body mass index of 18.5 to 24.9 kg/m2, getting at least 30 minutes of moderate to vigorous exercise daily, drinking alcohol moderately, and having a high healthy eating index score reduced all-cause mortality (−74%), cancer mortality (−65%), and cardiovascular mortality (−82%). Moderate alcohol was defined as 5 to 15 g/day for women and 5 to 30 g/day for men or one-third to one 12-oz beer for women and one-third to two 12-oz beers for men. It was not clear how the healthy eating score was calculated. These authors estimate that “adopting” all five of these health habits at age 50 would increase life expectancy 14.1 years for women and 12.1 years for men. — Circulation April 2018

Key ADA poster summaries include liraglutide in type 1 diabetes, oral semaglutide, bottled water’s association with type 2 diabetes, & SGLT-2 combo LIK066.

ADA 2018 abstracts of interest include Entresto for the Treatment of Diabetic Peripheral Neuropathy; Oral Contraceptive Associated with Postmenopausal Diabetes; Glucokinase as Adjunct Therapy in People with Type 1 Diabetes, and more.

Overview from a presentation at the 2018 American Diabetes Associations 78th Scientific Sessions.

The “artificial pancreas” provides glucose control for non-critically ill patients

A single dose of BCG vaccine appears to decrease progression of new onset diabetes.

Multiple testings still recommended for certain groups.

Quote of the Week!

“If we did all the things we are capable of, we would literally astound ourselves.”

…Thomas A. Edison

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletter:

Kaytie A. Weierstahl, Pharm.D. Candidate, LECOM School of Pharmacy

Amanda Cortes, PharmD Candidate, LECOM School of Pharmacy

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
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Ewing, NJ, 08628
USA
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