April 18, 2017 : DCMS #341

DISASTERS AVERTED — Near Miss Case Studies

There Is A Difference

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Michael Hill Part 4, System Safety

HOMERUN SLIDES — Great Clinical Presentation Highlights

 Albuminuria Presentation Part 7, Treating Kidney Disease

CLINICAL GEMS — The Best from Diabetes Texts

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #71: Regulation of Glucose Metabolism in Liver Part 7 of 11

MOST POPULAR ARTICLES OF THE MONTH

#1 New ADA 2017 Standards of Medical Care in Diabetes
#2 A Major Shift in Diabetes Treatment Targets and Goals
#3 Type 2 Diabetes Remission With Intensive Treatment

I recently spent some time talking to the director of one of the transplant centers in Florida that specializes in liver and kidney transplants. She was explaining all the the factors that go into finding a correct match for patients, how patients who need a kidney are selected and how something as small as an infection can take you from the top of the list to the bottom. This means that patients might miss the the right kidney and have to wait considerably longer for the organ transplant.

This is why managing chronic kidney disease is so important. This week, our Homerun Slides delve into ways of reducing and treating albuminuria.

Dave Joffe

Editor-in-chief

57-year-old female, prediabetes, class II obesity, arthritis R knee, family history includes father with type 2 diabetes with renal disease. Verbalizes her fear of having diabetes. Besides discussing lower carbohydrate meal plan, discussed metformin, and being as active as she possibly can without causing further injury to her knee. First set of labs showed her A1C to be 6.4% and her FPG 118.

In part 4 of this Exclusive Interview, Michael Hill explains the safety of the MiniMed 670G System and the results of the clinical trial, which included testing incidences of DKA and severe hypoglycemia requiring assistance.

In this week’s Homerun Slides, determining therapeutic approaches for patients with type 2 and chronic kidney disease.

Allosteric regulation of hexose flux is another example where the regulation of gluconeogenesis occurs by interaction with glycolytic regulation. The conversion of F-1-P to F-1,6-P2 is irreversibly catalyzed by the gluconeogenic enzyme fructose-1,6- bisphosphatase, and the opposite glycolytic reaction is irreversibly catalyzed by phosphofructokinase.

Psychological health, access to care, expanded and personalized treatment options and the tracking of hypoglycemia emphasized.

Out with the old, in with the old and new?

Theory proposed that type 2 diabetes can be reversed in the short term with medical approaches over bariatric surgeries.