April 23, 2016 : Issue #830

• Prediabetes: How Often is the Opportunity to Intervene Missed?
• Intensive Therapy for Type 1 Diabetes Cuts CVD Incidence by 30 Percent
• Can a Common Diabetes Drug Help Heart Attack Recovery?
• First-Ever Guidelines for Treating the Diabetic Foot
• Is Having A Younger Sibling A Factor That Can Prevent Diabetes in Later Life?
• Blood-Pressure Drug Could Be A Possible Type 1 Diabetes Cure

This week we find research on two old drugs for hypertension and  diabetes, but the interesting thing is that they may be changing places as to why we are using them.

It seems that the old calcium channel blocker, verapamil, may actually be able to save beta cells. Taking an old diabetes drug that most of us use every day is finally identified as a way to help heart attack victims recover. This will be good for the patients mentioned in Item 2 where we look at how they are benefiting from the education they received in the DCCT study.

Announcements:

Diabetes Summit 2016

DIC Publisher Steve Freed will be attending the GTCbio 2016 Diabetes Summit, to be held April 25-27, 2016 in Boston, MA.  This unique event encompasses the drug discovery and partnering aspects of diabetes in two individual conferences that take place concurrently. Click here for more information.

dLifeTV.com: Sunday, April 24, 7PM ET

From dLife.com: “Dr. Johnny White explains why how you think about your diabetes may be the most important key in controlling it. Also, Jim Turner’s devilish alter ego returns to crash a party, and Dr. Nat Strand talks animals and diabetes.” Sundays live online at dLifeTV.com at 7 PM ET, 6 PM CT, and 4 PM PT. Keep up on the latest dLife news at dLifeTV.com.

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We can make a difference!

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Dave Joffe, Editor-in-chief

Should a dentist or a periodontist be part of the diabetes team, along with the doctor, nurse, pharmacist, eye doctor and podiatrist? Follow the link to share your opinion – and see what your colleagues think!

LabStyle Innovations Corp., developer of the Dario™ Blood Glucose Monitoring System, announced that their all-in-one glucose monitoring system is now available directly from the manufacturer. The U.S. rollout follows the U.S. Food and Drug Administration’s 510(k) clearance of the Dario in December 2015.

Direct-to-consumer sales through LabStyle’s U.S. website at usa.mydario.com/shop are now available. LabStyle’s membership-based pricing for direct-to-consumer test strip sales offers users an effective and convenient solution. The Dario App is now also available through the App Store and ready for download by users across the U.S.

The Dario Blood Glucose Monitoring System consists of an all-in-one Smart Meter that plugs directly into smartphones coupled with a robust, real-time mobile app, that allows users to track and monitor data such as: blood glucose measurements, carbs and insulin intake, as well as physical activity directly on their mobile devices, making diabetes data management much simpler. Additionally, users can share this data with their community, family and medical staff.

Mr. Huang achieves good glycemic control with his lifestyle modifications, metformin and linaglipitin, and returns every 6 months for follow-up visits. Three years after initiating this treatment plan, he returns to your clinic for his 6-month check-up. When asked how his diabetes management is going at home, he shares that recently he has been “unable to really get out and get as much exercise as he know he should due to his creaky, old knees acting up.” His current office A1C is 8.8%. You discuss with him what the next management steps may be to achieve his individualized glycemic goal. What would your next medical management step be?

Select one answer:
A. Add a rapid-acting insulin analogue
B. Add a long-acting insulin analogue
C. Add a GLP-1 agonist
D. Add a sulfonylurea

Are you right? Follow the link to find out!

This is higher than previous estimates of 33%, and that number has now been shown to be 55% overall of those with diabetes or prediabetes, according to a UCLA study. Researchers analyzed data from the National Health and Nutrition Examination Survey and the California Health Interview Survey and found that the state’s prediabetes rates increase with age, from 33% of adults ages 18 to 39 to 60% of those ages 55 to 69. Now experts have data showing just how bleak the situation is. Rates of diabetes have increased more than 175% nationally since 1980, according to federal data. It’s now the seventh-leading cause of death in California.  About 90% of people with prediabetes are unaware of their condition, so most don’t get any treatment.  An often-cited clinical research study found that people with prediabetes who were overweight and improved their diet and worked out reduced their diabetes risk 58%. Those who instead took a medicine to treat diabetes reduced their risk only 31%.  National Health and Nutrition Examination Survey

Study finds less than one quarter of patients categorized as prediabetic received prediabetes treatment from their healthcare provider.

More than 30 years after the end of the DCCT study for type 1 diabetes, the benefits persist.

Better understanding of drug’s mechanism of action can lead the way to new treatment options for heart disease in diabetes patients.

The Society for Vascular Surgery, the American Podiatric Medical Association and the Society for Vascular Medicine collaboratively publish first-ever set of clinical practice guidelines for treating diabetic foot.

Study finds birth of younger sibling between 9 and 54 months decreases obesity odds for older sibling.

A common blood pressure drug is showing new promise to help treat and cure type 1 diabetes.

Quote of the Week!

“In order to carry a positive action we must develop here a positive vision.”

…Dalai Lama

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletter:

Renata Kulawik, LECOM College of Pharmacy

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
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Ewing, NJ, 08628
USA
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