Lifestyle, Metformin, Delay Diabetes

New data from the ongoing US Diabetes Prevention Program (DPP) show that randomizing overweight or obese people at high risk for type 2 diabetes to intensive lifestyle change or giving them the oral agent metformin can reduce or delay the development of the disease for as long as 15 years. Although 50% of the approximately 3000 participants did become diabetic over the time course, "the results show that diabetes is not inevitable in people at high risk; we established that it can be prevented or delayed. American Diabetes Association 2014 Scientific Sessions