Study assesses the prevalence of complications following regular use of cannabis.

Variations in certain macronutrients may be correlated to change in insulin sensitivity/resistance.

GLP-1 treatment benefits patients on statins and with varying LDL levels.

New study shows implementing tighter treatment goals for GDM does not improve birth weight in neonates, but may increase risk for earlier birth and clinician intervention.

Study focuses on score accuracy to improve prediction models for the better.

John S. is a 63-year-old white man with significant abdominal obesity, type 2 diabetes, hypertension, and dyslipidemia as well. On the basis of an exercise stress test, John was recently diagnosed with silent ischemia. John’s current medications include metformin, a DPP-4 inhibitor, an ACE inhibitor/HCTZ agent, a calcium channel blocker, a high-dose statin, and ezetimibe. John’s relevant physical exam and laboratory findings are as follows:

BMI: 34.8 kg/m2
Blood pressure: 140/86 mm Hg
HbA1C: 7.2%
Total cholesterol: 150 mg/dL
LDL-C: 79 mg/dL
HDL-C: 42 mg/dL
Triglycerides: 145 mg/dL
non-HDL-C: 118 mg/dL
eGFR: 65 mL/min/1.73 m2
ACR: 100 mg albumin/g creatinine

Which statement best describes the evidence supporting cardiovascular benefits of the antihyperglycemic agents available to treat John’s type 2 diabetes?

A. Further glucose reduction using any available agent should have similar cardiovascular disease benefit.
B. Thiazolidinediones increase the risk of heart failure and myocardial infarction in patients with type 2 diabetes.
C. Two approved GLP-1 receptor agonists have been shown to reduce mortality in patients with type 2 diabetes and cardiovascular disease.
D. Both GLP-1 receptor agonists and SGLT2 inhibitors affect cardiovascular risk through the same physiologic mechanisms.

Follow the link for the answer.

With all the new insulin pump technology, do you feel that more patients, with either type 1 or type 2 using insulin, will move towards the smart pump rather than an insulin pump? Follow the link to see how you compare to your colleagues.

Young adults cite fear of complications, burden of disease management, impact on family and job

Significant association for men, with positive but not statistically significant link seen for women

Prediction independent of traditional risk factors such as MetS, glucose, HbA1c in general population