The role of beta-cell death and regeneration: The loss of beta-cells in T2DM has been mainly attributed to increased beta-cell death due to apoptosis and other forms of cell death, possibly driven by adverse environmental conditions and probably mediated by several intracellular mechanisms. Apoptosis is a type of programmed cell death morphologically characterized by cell rounding up, bleb formation and chromatin condensation. As a matter of fact, in autoptic pancreatic samples apoptosis has been shown to be significantly increased in both obese and lean type 2 diabetic cases as compared to BMI-matched, nondiabetic controls.

Decrease in length of stay and mortality, but increase in mean hospital charges during study period

Docs describe burnout and emotional exhaustion; moral distress at seeing suffering and injustice

The once-weekly glucagon-like peptide 1 receptor agonist cuts HbA1c, body weight

The once-weekly glucagon-like peptide 1 receptor agonist cuts HbA1c, body weight

Sometimes you wonder why logical thinking is often left out in medical care. Way back in the last century, when I was learning about diabetes, its causes, and solutions, it seemed logical that if you eat less sugar you will need less insulin if you are type 1, and less …

Low carbs equals lower blood sugars and control, with less hypoglycemia, but how low do our patients need to go?

Pooled analysis from two randomized trials shows significant differences in effects on two groups.

Study looks at whether intensive BP lowering can increase the risk of CKD.

According to a recent published study, HbA1c variability is a better predictor of mortality in patients with type 2 diabetes compared with HbA1c averages.