All of us are familiar with the value of SGLT-2 Inhibitors, and when we talk to patients we focus on the decreased re-absorption of glucose in the kidney and how that equals a decrease of about 70-100 carbs a day. However, if you add a GLP-1 analog it is possible …

In pooled analyses, no clinically relevant between-group difference in bone mineral density at any site

Findings based on data reweighted to reflect the adult population with diabetes in the U.S.

Among obese teens, most rapid weight gain happened in childhood between ages 2 and 6

Additional focus on lifestyle management, self-management education and support emphasized

This week I got a new update from 23 and Me. They had some new data on the effects of gene mutations on major disease and when I looked up diabetes they let me know…based on a few large studies, it is estimated that 30-80% of the risk of developing …

Male, 69 years of age, coronary artery disease,  two cardiac stents, hypertension, hyperlipidemia, prediabetes, bladder cancer.  His sister is 64 years of age, coronary artery disease, prediabetes, PCOS, elevated cardiac calcium score of >1000, no hyperlipidemia. HO early heart disease, stroke, and early death in family. There have been recent reports in the media speaking of the ASPREE Trial, which reported that taking aspirin daily is not effective for all people, and in some it may be more detrimental due to bleeding risks.

Lisa Letourneau, MPH, RD, LDN, is a diabetes researcher, dietitian, and public health professional. As Diabetes and Genetics Clinical Research Manager at the University of Chicago, her work focuses on managing multiple studies related to atypical diabetes, including the largest monogenic diabetes registry in the United States.

In this week's Homerun Slides, we bring you the first question in little game to test your endocrinology knowledge, from a recent presentation by Dr. Claude Lardinois. For (a fictional) $100, this was discovered as part of an evaluation for headaches.

Chronic hyperglycemia as a cause of insulin Resistance: Insulin resistance in patients with type 1 diabetes—a consequence of glucose toxicity? Insulin resistance both precedes and predicts type 2 diabetes and therefore is not merely due to hyperglycemia. In the case of type 1 diabetes, it is clear that insulin resistance is an acquired and reversible phenomenon since insulin sensitivity is completely normalized during remission of the disease.