In this week's Homerun Slides, round 3 in the pituitary category from Dr. Claude Lardinois' Endocrinology Jeopardy. This week's clue is visual, so click to see what it is!

The hexosamine/O-linked N-acetyl glucosamine pathway: One metabolic fate of glucose is the hexosamine biosynthetic pathway (HBP), and high flux through this pathway, such as occurs in diabetes or overnutrition, has been convincingly linked to insulin resistance and beta-cell failure. In this pathway a relatively small fraction of cellular glucose flux—a few percent in most tissues—is converted to UDP-N-acetylglucosamine (UDP-GlcNAc) and other amino sugars. The rate limiting step is catalyzed by the enzyme glutamine: fructose-6-phosphate amidotransferase (GFA) that catalyzes the synthesis of glucosamine-6-P from fructose-6-P and glutamine.

In this Exclusive Interview transcript, Sylvia Ley talks with Diabetes in Control publisher Steve Freed during the ADA 2018 convention in Orlando about why eating red meat, especially processed red meat, increases risk for diabetes.

In this Exclusive Interview, Sylvia Ley talks with Diabetes in Control publisher Steve Freed during the ADA 2018 convention in Orlando about the concerns of eating processed red meat, especially for people at risk for developing diabetes.

In part 1 of this Exclusive Interview, Sylvia Ley talks with Diabetes in Control Publisher Steve Freed about the difference between red meat and processed red meat, and the implications for consuming either.

In part 2 of this Exclusive Interview, Sylvia Ley talks with Diabetes in Control Publisher Steve Freed about the impact of using high heat when cooking meat and the cancer implications.

In part 3 of this Exclusive Interview, Sylvia Ley talks with Diabetes in Control Publisher Steve Freed about her overall message of a balanced, all-encompassing diet for people with diabetes, as recommended by medical experts.

In part 4, the conclusion of this Exclusive Interview, Sylvia Ley talks with Diabetes in Control Publisher Steve Freed about alternative proteins that are healthier options for people with diabetes.

Large gap between costs, projected reimbursement for Medicare Diabetes Prevention Program

Based on long-term follow-up, percent regain after max weight loss tied to most health outcomes