Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for October 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.Link Between …

High-dose IV iron administered proactively is noninferior to low-dose iron administered reactively

Strict BP control, fenofibrate use may increase long-term risk for adverse kidney events in T2DM patients

The Annual Meeting of the American Society of Nephrology, Kidney Week 2018Kidney Week, the annual meeting of the American Society of Nephrology, was held from Oct. 23 to 28 in San Diego and attracted approximately 13,000 participants from around the world, including nephrology specialists, researchers, scientists, and other health care …

Significant improvements observed in emotional and physical well-being, depression, quality of life, HbA1c

A few years back, I was working with an endocrinologist in St. Petersburg, managing his diabetes patients. We would get a lot of type 2 patients who had been started on basal insulin and then referred to us when their condition required the addition of mealtime insulin. Most of these …

Michael S. Irwig, MD, F.A.C.E., is board-certified in Endocrinology & Metabolism and is an associate professor of Medicine at The George Washington University School of Medicine & Health Sciences. He also is an adjunct associate professor of Medicine at Georgetown University School of Medicine.

In this week's Homerun Slides, we begin a new series showing the value of continuous glucose monitoring.

The effects are consistent with a role for O-GlcNAc in damping acute hormone- and phosphorylation-mediated signals in situations of chronic nutrient excess. Although discovered in the context of diabetes, the aforementioned changes mediated by the HBP can also be viewed as adaptive responses to excess nutrient flux: muscle cells protect themselves from excess glucose fluxes and the excess nutrients are eventually stored as fat. Indeed, if insulin signaling were not dampened and glycogen synthesis were effectively engaged even with overeating, a pound of ingested carbohydrate would result in approximately four pounds of hydrated glycogen in muscle, and it is easy to visualize diets rich in sodas and donuts resulting in the development of glycogen storage diseases.

In this Exclusive Interview transcript, Michael Irwig talks with Diabetes in Control publisher Steve Freed during the AACE 2018 convention in Boston about treating low testosterone and how diabetes and obesity can affect testosterone levels.