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Yearly Archives: 2017

Aug. 8, 2017

When it comes to diabetes, there seems to be a thousand right ways to get your patients to lose weight. While weight loss is only one component of managing diabetes, it is often the most quoted and hardest to do. This week in Part 4 of our Exclusive Interview with …

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #85: Measuring Insulin Action In Vivo

Insulin action dynamics: Insulin sensitivity from the clamp is expressed in terms of the steady-state value reached after a period of hyperinsulinemia. A dose–response can be constructed and sensitivity can be expressed as the ED50, that is, the concentration for half-maximal stimulation of Rd as a function of dose. Alternatively, sensitivity can be expressed (as it usually is) as the Rd at a specific dose of insulin, which may be low, intermediate, or a maximum dose. It is often assumed that steady-state rate of glucose uptake is reached by 180 min after onset of the insulin infusion. In fact, steady-state glucose uptake is not reached at 3h. Glucose uptake rate at 3h is only 2/3 the “true” steady-state, which is not achieved until 6h. Certainly, shorter periods (e.g. 120 min) are inadequate to reflect steady-state rates of uptake.

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Aug. 5, 2017

Many of us know diabetes professionals who have diabetes and that was a driving force in choosing their profession. If you look on our board of adv isors you will find some of those very professionals. One of them is Dr. Sheri Colberg, who has been working with us for …

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…And Stay Active: A Profile in Living Successfully with Diabetes

I have been writing columns—mostly about physical activity and exercise—for this enewsletter for more than a decade, and I am grateful to DIC for allowing me to educate everyone on topics that I feel so strongly about. This month, I would like to switch gears a bit and share some of my personal story about why physical activity matters to me and how I have lived successfully with type 1 diabetes for almost 50 years to date.

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