In this week's Homerun Slides, schema of the action of the Glycocalyx.

Insulin sensitivity based upon the OGTT: The previous discussion suggests that “quick and dirty” indices from fasting values may not be accurate, and it is often true that laboratory procedures are impractical. Recently, it has been suggested that indices calculated from the OGTT may be useful for population studies. For decades the OGTT has been used as a screening test and a diagnostic tool for diabetes and IGT. It might be ideal if one could classify the state of carbohydrate tolerance and simultaneously measure insulin sensitivity and beta-cell function.

It was not uncommon a few years ago to take a patient off metformin when they went on insulin. Metformin was considered a type 2 drug and when someone either had type 1 or they became insulin dependent there was no real value for metformin. I spent 13 years working …

Semaglutide trumps Trulicity in most recent trial.

The evolution of metformin therapy through the decades.

Diabetic foot ulcers put patients at increased risk of falling.

CKD risk not necessarily tied to albuminuria in patients with type 1 diabetes.

Lowering HbA1c worth the risk of urinary tract and genital infections?

Your patient has been newly diagnosed with type 2 diabetes (A1C 7.7%) and you have prescribed metformin. Metformin should be titrated to minimize which side effect? A. Rebound hyperglycemia B. Reactive hypoglycemia C. Weight gain D. Gastrointestinal-side effects Follow the link to see the answer.

How often do you recommend to your type 2 patients who are not on insulin to monitor their blood sugars daily? 1. Once a day 2. Twice a day 3. More than twice a day 4. Once a week or Less than daily Follow the link to share your response.