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Monthly Archives: July 2017

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #81: Insulin Actions In Vivo: Glucose Metabolism Part 7 of 9

Cellular, biochemical, and molecular mechanisms of insulin action: The insulin receptor is a glycoprotein consisting of two alpha subunits and two beta subunits linked by disulfide bonds and expresses insulin-stimulated kinase activity directed towards its own tyrosine residues. Insulin receptor phosphorylation of the α subunit, with subsequent activation of insulin receptor tyrosine kinase, represents the first step in the action of insulin on glucose metabolism.

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July 1, 2017

It is not how often you take your glucose, but rather when you take your glucose reading, that makes the biggest difference. For many years the standard of care has been for an orally medicated patient to check their glucose when they first get up in the morning. Two things occur …

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Statins and Exercise: Revisited

I chronicled someone with type 1 diabetes whose ability to exercise was compromised by his use of statins back in April 2016. As you know, statins are a class of medications prescribed to lower cholesterol levels or abnormal levels of blood fats, with the goal being a reduction in the risk of heart attack and stroke. Brand name examples of statin medications include Altoprev, Crestor, Lescol, Lipitor, Livalo, Mevacor, Pravachol, and Zocor.

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