I had the good fortune of attending a Children with Diabetes conference some 10 years ago at Disney World in Orlando. During this conference, many of the kids had been keeping their insulin in their room refrigerators. One morning, some of the kids woke to find their insulin either frozen …

I have type 1 diabetes and have been living with it for the past 11 years. I take daily insulin injections to stay alive and well. A couple of years ago, I had a very frustrating incident when my insulin stopped working. I began injecting loads of insulin, and even with multiple doses my blood glucose wouldn’t drop.

Dr. Hartman discusses diabetes, hyperlipidemia and obesity, and why it is crucial to treat obesity as a clinical condition, not a willpower issue.

In this Exclusive Interview, Dr. Hartman discuss practical points in the approach of the patient with diabetes, hyperlipidemia and obesity.

In this week's Homerun Slides, the initiation of basal insulin.

Intravenous glucose: In the presence of euglycemia, insulin displays a potent suppressive action on hepatic glucose production, such that portal insulin concentrations of less than 100 mU L−1 abolish glucose entry into the circulation. Figure 14.7 shows a typical time course for endogenous glucose production following an acute increase in plasma insulin to levels of 60 – 70 mU L−1 in a healthy subject.