We often spend a lot of time looking for more ways for our patients to burn energy if they are overweight and use less energy if they are lean. This seems like a simple process of food in, energy out, but it never seems easy when we work on the …

Male, 62 years of age, type 2 diabetes, class III obesity. Has been on metformin, 1,000mg twice daily. Glucose in the 200-300mg/dL range. A1C. Taught about lower carb meal plan, started on Trulicity, first 0.75mg, then 1.5mg/dL. Made the dietary changes right away with the addition of the Trulicity. Within 2 weeks glucose levels averaged 125, patient losing weight, decreased appetite and feeling good. More energy. Insurance did not cover Trulicity, but did cover Victoza, so started on Victoza. When made the change, started with the 0.6mg daily, then increased weekly to the 1.8mg/day.

In this Exclusive Interview, Dr. Calderella gives tips for the patient and the health care provider on preparing for pregnancy and what to do if diagnosed after pregnancy.

Dr. Felice Caldarella shares insights on how healthcare providers and patients can cope with a diagnosis of diabetes in pregnancy.

In this week's Homerun Slides, a summary of the clinical trials assessing the impact of intensive therapy in type 2 diabetes.

Glucose disposal: In the basal state, steady/near steady-state conditions prevail and whole-body glucose disposal equals endogenous (hepatic) plus renal glucose production. Data on the individual contribution of organs and tissues to total glucose uptake have been obtained in regional catheterization studies. In the case of the splanchnic area, in which glucose uptake and production both occur simultaneously, such data have been derived from the combined use of glucose tracers and indwelling catheters.