Home / 2017 / May / 23

Daily Archives: May 23, 2017

May 23, 2017

There has been a lot of press lately about the high cost of insulin, and even Congress has called the leaders of insulin companies to task for the prices. Some of the companies have linked up with discount programs like Blink to make insulin more affordable, and the companies themselves …

Read More »

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #75: Insulin actions in vivo: glucose metabolism Part 1 of 9

Glucose is widespread in living organisms and, with protein and fat, completes the triad of the major metabolic fuels. To a much lesser extent than in plants, glucose also constitutes a building block for structural and enzymatic components of cells as well as the extracellular matrix. As a metabolic substrate, glucose is present in organisms essentially in its simple, monomeric form (alpha-D-glucopyranose) and as a branched polymer of alpha-glucose, namely glycogen. Disaccharides of glucose (lactose, maltose, and sucrose) are quantitatively less important. Glucose is present in plasma water at a concentration that — in a healthy adult who has fasted overnight — ranges between 3.6 and 5.5 mmol L−1 (65 – 99 mg dL−1 ).

Read More »