The DPP-IV inhibitor sitagliptin was safe and effective over 3 years for adults aged at least 75 years who had well-controlled type 2 diabetes and cardiovascular disease, findings from an analysis of TECOS study data show.

We know from previous studies that obesity and type 2 diabetes are associated with vascular stiffening and the development of cardiovascular disease.

A DPP-4 inhibitor can help to prevent kidney function and did not have any negative cardiovascular effects.

When we explain to a patient how insulin release occurs, we often oversimplify it. We tell them that the release is caused by signals sent to the beta cells when food enters our body. We often add in the “simplicity” of, if you eat the right foods your pancreas will …

When we think about disasters, we usually think of the outcome, a poor health outcome. We don’t always think about the journey. The journey to poor health outcomes are many. Today I am reminded of not having the insurance coverage for the correct medication. Without it, one can have a disaster, poor diabetes management. The consequences of that, as well as the disruption to running a smooth office.

Dr. Altamash Shaikh talks with Diabetes in Control Associate Medical Editor Joy Pape at the 2016 AACE Meeting. In part 2 of this Exclusive Interview, Dr. Shaik explains the pervasiveness of diabetes among the younger Indian population and the three reasons for this occurrence.

In this week's Homerun Slides, the cardiovascular outcomes of patients in the placebo vs empagliflozin study.

Insulin receptors, ligand binding: The insulin action sequence is initiated with specific binding to high-affinity receptors on the plasma membrane of target cells. The insulin receptor is a large transmembrane glycoprotein consisting of two alpha- and two beta- subunits that form a heterotetramer, as depicted in Figure 12.1. The insulin receptor is synthesized from a single gene as a polypeptide pro receptor comprised of alpha- and beta- subunit sequences in tandem.

This past Thursday, Congress passed a resolution to begin the dismantling of the Affordable Care Act. If you remember, many of the candidates, including the president-elect, touted this as their first act if they won the election. Now that they have made the first move, you have to wonder if …

Can we answer the question of how you can have a pre-disease that increases your risk of death? You either have it or you don’t!