On Monday, the FDA gave approval to NovoNordisk’s new combination product, Xultophy. This is a combination of the super long-acting insulin degludec and the once daily GLP-1 agonist Liraglutide. The fixed dose combination is given in one to 50 dosing steps to maximize to glycemic control. The super long-acting insulin …
Read More »Monthly Archives: November 2016
Some Blood Glucose Number is Better than No Number
In my experience, most people will check their fasting glucose levels, but due to time, place, not enough strips, or just the fact they don’t want to see…many will not check after eating. For those who will only check once a day, I recommend alternating a fasting blood glucose check with a bedtime blood glucose check.
Read More »Dr. Jeffrey Mechanick Part 4, Influx of Prediabetes Patients
Dr. Jeffrey Mechanick talks with Diabetes in Control Publisher Steve Freed at the 2016 AACE Meeting. In part 4 of this Exclusive Interview, Dr. Mechanick explains the improved understanding of the need for the expertise of an endocrinologist in helping the prediabetes patient.
Read More »Continuous Glucose Monitoring in the Hospital Part 3
In this week's Homerun Slides, the ideal glucose sensor for clinical care.
Read More »International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #51: Incretin Physiology in Health and Disease Part 1 of 6
The incretin effect in health: The idea that gastrointestinal factors contribute to the control of postprandial glucose regulation dates back to the beginning of the twentieth century, when Moore and colleagues reported reductions in glucosuria after the oral administration of gut extracts xin patients with juvenile diabetes. Even though it is questionable whether these glucose-lowering effects were really attributable to the incretin activity of the extract (which is unlikely, because most gastrointestinal peptide hormones are inactivated by the gastric acid), this report can be considered as the first description of an incretin-like effect.
Read More »Nov. 19, 2016
Recently I got to spend some time with the director of a kidney / liver transplant center in Largo, Fl. While I was touring the facility she was telling me about how they select candidates for kidney transplant, and the problems that keep people from being selected. We also talked …
Read More »Renal Outcomes With DPP-4 Inhibitors, SGLT-2s, and GLP-1 Agonists
Data from 2 trials show long-term use can improve albumin/creatinine ratio, but not other renal outcomes.
Read More »Losing Weight Increases Hunger
New study finds that when you lose weight, you will consume more calories than necessary to maintain the lower weight.
Read More »Belly Fat Risk for CVD Worse than We Thought
One type of belly fat may be more risky, according to results from an imaging-based study.
Read More »Can Statins Offset Insulin-Related Cancer Risk in T2DM?
Greater risk reduction in those not receiving antihyperglycemic treatment.
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