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Daily Archives: Aug 23, 2016

August 23, 2016

Last week, I had a new patient referred to me with adult onset type 1 diabetes. The patient was 63 years old and — although she had been losing weight over the past year — it was a 16 pound loss over the previous 2 weeks that got the physician concerned. An A1c test came …

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When There’s Water, Check the Shoes

People who have diabetes are usually taught to purchase protective soft leather shoes with a wide toe box. That doesn’t mean everybody who has diabetes follows those recommendations. A woman, type 2 diabetes, who is knowledgeable about diabetes and foot complications was wearing cloth shoes with a “corded” bottom and manmade rubber sole. She was caught in the rain. Her shoes were soaked.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #38: Normal Beta-cell Function Part 3 of 6

Beta-Cell response to nonglucose secretagogues: Proteins and amino acids -- The insulinotropic effect of oral proteins was first described almost 50 years ago and recently confirmed. After the ingestion of a small amount of proteins (30–50 g) or a larger amount of proteins (2 g kg−1), plasma insulin was raised two- to threefold over baseline and remained persistently elevated for 90 or 240 minutes, respectively. In either case, blood glucose did not change, whereas both GLP-1 and GIP levels were raised threefold over fasting values.

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