In this week's Homerun Slides, the cost of the current diabetes classification.

Dysregulation of the insulin gene: There is convincing evidence that abnormalities in insulin gene sequence or function play a role in pancreatic beta-cell dysfunction in type 2 diabetes. Abnormalities in the insulin gene structure consist of rare control region mutations, while insulin gene expression appears to be reduced by metabolic conditions associated with the diabetic state.

I was watching “Beyond the Tank” on TV last week. For those of you who are not familiar with that show, it is a followup to “Shark Tank” and looks at how businesses that the Sharks invested in are doing months later. This episode focused on Mission Belt company and …

New guidelines cite effectiveness, cost efficiency, and safety as reasons to consider procedure.

Study shows the SGLT-2 inhibitor can lower HbA1c, BP, and weight in T2DM patients.

New FDA nutrition facts label aims to make it easier for consumers to make informed choices about what they’re eating.

FDA issues alert about interim safety results from ongoing clinical trial, but study of potential canagliflozin amputation risk is ongoing.

Higher level of cardiorespiratory fitness (CRF) over two decades was shown to reduce risk for developing prediabetes and T2, even after adjusting for changes in BMI.

A recent study published in Obesity in May 2016 reported very discouraging findings for a group of participants who had lost weight on “The Biggest Loser” (TBL) reality TV show: not only did almost all of them regain a significant amount of weight over the 6-year period following the show, but they also had lower resting metabolic rates than expected for their body weights, even six years later. With the way the media ran with this story, it will not be a surprise if everyone just gives up staying thinner and blames excess weight on a faulty, and unchangeable, metabolism.

With over 33,000 yearly accidental deaths from guns, should medical professionals have the responsibility to talk about safety to their patients who own guns? Follow the link to respond -- and to see what others think.