Woman, 67 years of age, newly diagnosed with type 2 diabetes with an A1C of 7.8%. Met with PCP who prescribed metformin ER and referred patient for diabetes education. Patient made some dietary and physical activity changes at first, but upon return visit her A1C was 8.5%. She reported she did not take the metformin. “I can’t swallow big pills. The bottle said not to crush or break the tablets. They were just too big to swallow. So then I just gave up on everything.”

In this week's Homerun Slides, targets and therapies for type 2 diabetes based on patient characteristics and A1C.

Age- and sex-specific prevalence of type 2 diabetes in different ethnic groups: Type 2 diabetes mellitus (T2DM) is now taking its place as one of the main threats to human health in the twenty-first century. In 1921, Dr Elliot Joslin was already concerned that according to his count there had been a doubling of diabetes in three decades. The impact of T2DM is increasingly felt around the world, with its prevalence rising dramatically over recent decades.

In part 3 of this Exclusive Interview, Dr. Rhinehart shares his thoughts with DIC publisher Steve Freed on the benefits of SGLT-2 and GLP-1s. What do these new medications offer when it comes to costs, side effects and staying on top of the research to help facilitate use in the right patients?

New study shows recent improvement in years of life lost.

New animal study shows the effects of empagliflozin, an SGLT-2 inhibitor, on the pancreatic cells of mice.

New research suggests that a healthy lifestyle is better than any medicine out there.

Endoscopic sleeve gastroplasty may be the answer to the obesity epidemic.

Water dispenser study examined whether availability of water would reduce soda consumption, obesity rates.

Nutrients found in lemon zest, specifically polyphenols, can help improve insulin resistance.