Combination of insulin, a GLP-1 receptor agonist and an SGLT-2 inhibitor effective, includes DKA risk.
Read More »Yearly Archives: 2015
Partners and Spouses Have Double Diabetes Risk
Spouses or live-in partners of people newly diagnosed with diabetes twice as likely to develop diabetes…
Read More »Investigational Drug ITCA 650, a GLP-1 Receptor Agonist, on the Way
Drug shows a significant reduction in HbA1c in patients with type 2 diabetes… A new investigational drug is underway to help with reduction of HbA1c, weight, and improve glycemic control in type 2 diabetes patients. ITCA 650 is an injection-free GLP-1 receptor agonist that provides continuous subcutaneous exenatide for 12 …
Read More »Lilly Insulin: A Better Alternative than Lantus?
Peglispro allows slow insulin absorption, but associated with injection site reaction and increased ALT and triglycerides… Peglispro or pegylated lispro insulin is currently under phase III investigation for both type 1 and type 2 diabetes. The large hydrodynamic size of peglispro allows slow insulin absorption and reduces clearance, resulting in …
Read More »No Association Between Sulfonylurea Use and Cardiovascular Mortality
Sulfonylureas not associated with increased cardiovascular mortality, myocardial infarction and stroke in a meta-analysis of 47 randomized clinical trials… Sulfonylureas are relatively inexpensive and are important therapeutic agents in type 2 diabetes management. However, they are not widely used due to safety concerns regarding hypoglycemia and weight gain. Furthermore, it …
Read More »Panel Recommends Two Cholesterol-lowering Drugs for FDA Approval
The two new injectable drugs, alirocumab and evolocumub, have been recommended for FDA approval by the agency’s Endocrinologic and Metabolic Advisory Committee.…
Read More »Using LixiLan Does Not Increase Hypoglycemia
Fixed-dose insulin glargine/lixisenatide improves HbA1c levels in patients with type 2 diabetes…
Read More »Dulaglutide over Insulin Glargine in the Reduction of HbA1c?
GLP-1 analog also showed reduction in weight and incidence of hypoglycemia… Dulaglutide (Trulicity) is a glucagon-like peptide analog that is used once weekly to improve blood glucose level. During the open-label, multinational, parallel arm study, researchers compared the safety and efficacy of dulaglutide 0.75mg and 1.5mg to insulin glargine in …
Read More »Substandard Care for Diabetes in Diabetes Clinics
Diabetes subspecialty and primary care clinics showed low control rates of A1C, LDL cholesterol and microalbuminuria, compared with family practice and internal medicine clinics, according to a study. While the rates of HbA1c, LDL-cholesterol and microalbuminuria testing appear to be high in both diabetes subspecialty and primary care clinics, the …
Read More »Eating Just a Handful of Nuts Daily Lowers Risk of Death from Diseases
Previous research has hailed peanuts and nuts for their health benefits. Now, a new study supports such research, finding that consuming these foods may protect against death from numerous diseases, including cancer, heart disease and diabetes. The study results revealed that participants who consumed around 15 grams of nuts or …
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