This matchstick-sized pump — currently called the ITCA 650 (Intarcia Therapeutics; Boston, Massachusetts) — could replace pills and injections for type 2 diabetes. It’s implanted under the skin of the abdomen and releases doses of the glucagon-like peptide-1 agonist exenatide (Bydureon®, Byetta®) to help control blood glucose. It must …
Read More »Monthly Archives: April 2015
Intarcia Therapeutics Raises Funds for Pump Development
Intarcia Therapeutics was able to raise an additional $225 million to continue their development and commercialization of an implantable pump that delivers a year’s supply of exenatide. See Product of the Week.
Read More »Editor’s Note, SGLT-2 Inhibitor Special Edition, April 2015
Beta cells are very important in the production of insulin as we all know, and when our patients are developing diabetes they actually turn up insulin production in the beta cells, so that when they are diagnosed many patients are actually making a lot of insulin. However this overproduction of …
Read More »Editor’s Desk, DCMS #238
It seems that patients often fall into two categories when they get diagnosed with diabetes. They either get serious and try to do everything to reverse their disease or they just ignore it and figure it will go away. This week our Clinical Mastery Series newsletter looks at both categories. …
Read More »Joseph Houmard, PhD: Aerobic vs. Resistance Exercise
Joseph Hourmard talks about the benefits of aerobic exercise versus anaerobic exercise, and notes that as patients get older, doing more resistance-type exercise will help to maintain muscle mass. However, he again points out that the best exercise is the type that patients will actually do. He also notes that …
Read More »ADA 2015 Guidelines, Part 1
In this week’s Homerun Slides, we begin a short 5-part series covering the latest guidelines from the ADA. Topics covered this week include the Criteria for Diabetes Diagnosis, Categories for Increased Risk in Diabetes, and Screening Children for Type 2 Diabetes and Prediabetes…. To download the complete set of slides …
Read More »Letter from the Editor, #779
For years we at Diabetes in Control have advocated a lower carbohydrate diet with protein and fat increases to manage diabetes. Over time many mainstream organizations and diabetes care facilities have adjusted their thinking and one of our long term advisory board members, Dr. Richard Bernstein, is no longer ostracized …
Read More »Oral Insulin May Prevent Type 1 Diabetes in High-Risk Children
In the Pre-POINT pilot study, five of six children who were at extremely high risk of developing type 1 diabetes and who received a high dose of oral insulin had a protective immune response, and the insulin did not cause hypoglycemia… Children at risk for type 1 diabetes, who were …
Read More »Preventing Major Cardiovascular Events in Diabetics
Controlling factors such as HbA1c, LDL cholesterol, blood pressure, and smoking can all help to reduce risk… Researchers assessed the incidence of major cardiovascular (CV) hospitalization events and all-cause deaths among adults with diabetes with or without CV disease (CVD) associated with inadequately controlled glycated hemoglobin (A1C), high LDL cholesterol …
Read More »Statin Therapy Associated with 46% Higher Risk of Type 2 Diabetes
According to a new study, statin therapy may increase the risk of type 2 diabetes by decreasing insulin sensitivity and secretion… Statins are considered to be safe and well-tolerated medications commonly used for the prevention of cardiovascular disease (CVD) events in individuals with and without diabetes. However, recent studies showed …
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