This might be a reason not to use a DPP-4 for those with long standing diabetes… Reduction in the glucose-regulating hormone glucagon-like peptide-1 (GLP-1) appears to occur before the development of type 2 diabetes and obesity, according to new published research. Investigator Kristine Færch, PhD, senior research fellow at the …

By closely examining currently used diagnostic criteria, researchers evaluated whether it might be possible to diagnose type 1 earlier…. Today, diagnostic criteria for type 1 diabetes includes a glucose value ≥ 126 mg/dL and 2-h glucose values ≥ 200 mg/dL. These glucose values were selected because they correspond with observed …

Mice treated with DPP-4 inhibitors also showed an increase in production of their own glucagon… Siri Malmgren, a researcher at Lund University, stated that, “If these inhibitors also prove effective in humans against low blood sugar, then this supports the idea that the area of application of these drugs could …

Dental visits may allow for diabetes screening and monitoring glucose control in at-risk patients… A new study suggests that using gingival crevicular blood, collected during dental visits, for HbA1c testing produced values that were nearly identical to those obtained using finger stick blood. Correlation was 0.991 between the HbA1c values …

It may be possible to predict the development of type 1 diabetes in young children by measuring the presence of autoantibodies in the blood… This comes from new data from The Environmental Determinants of Diabetes in the Young (TEDDY) study. Lead researcher Åke Lernmark, MD, PhD, of Lund University, said …

Sanofi hoping to convert patients to Toujeo as Lantus is due to lose U.S. patent protection.

In December, the ADA reduced its BMI threshold for diagnosing type 2 diabetes in Asian Americans to ≥23 kg/m2.…

Low vitamin D levels associated with larger brain infarct volume and worse outcomes in patients with ischemic strokes….

Targeted strategies needed to prevent obesity in women of childbearing age, says the DORIAN consortium… The Developmental ORIgins of healthy and unhealthy AgeiNg: the role of maternal obesity (DORIAN) consortium, funded by the European Commission’s Framework Programme 7, has released results gathered from its 3 year research programme which began …

Phosphatidylcholine is a chemical contained in eggs, soybeans, mustard, sunflower, and other foods… Researchers included data on dietary intake from three observational cohorts; the Nurses’ Health Study (NHS), NHS II, and the Health Professionals Follow-Up Study (HPFS). The authors excluded participants with diabetes, cardiovascular disease, cancer, or unlikely dietary data …