Approved as an adjunctive treatment to diet and exercise for adults with type 2 diabetes… The once-daily tablet is the first in the United States to combine a sodium glucose cotransporter 2 (SGLT2) inhibitor (empagliflozin) with a dipeptidyl peptidase-4 (DPP-4) inhibitor (linagliptin). The tablets contain 10 or 25 mg of …
Read More »Monthly Archives: February 2015
Abnormal Glucose Tolerance Is Increasing in Sub-Saharan Africans
According to the International Diabetes Federation, by the year 2035, 41.5 million sub-Saharan Africans will be diagnosed as diabetics and 66 million will be diagnosed as pre-diabetics… This is a 100% increase in the occurrence of diabetes, and it’s the highest predicted increase in the world. To find out whether …
Read More »Measuring CKD and Cognitive Impairment in Type 2 African Americans
Participants with CKD had significantly poorer processing speed and working memory…. Both type 2 diabetes and chronic kidney disease (CKD) have been associated with structural brain changes. In previous studies, people with type 2 diabetes have been shown to have reduced total gray matter and WM volume, as well as …
Read More »A Probiotic That Helps Control Diabetes
Cornell University scientists engineered a strain of lactobacillus to secrete a GLP-1 that lowered blood glucose levels…. Science may be one step closer to treating diabetes with a human probiotic pill, according to new research. In the study, the researchers engineered a strain of lactobacillus, a human probiotic common in …
Read More »Maternal Glycemia Linked to Childhood Obesity
Maternal obesity and Hispanic ethnicity were found to be most associated with childhood obesity and metabolic dysfunction…. A secondary analysis of a mild gestational diabetes mellitus treatment trial long-term follow-up study looked at the relationship between maternal oral glucose tolerance testing and childhood body mass index, fasting glucose, insulin and …
Read More »More Leisure-time Physical Activity Results in Less Short-term Cardiovascular Risk in CAD Patients
Both patients with and without diabetes but with thrice-weekly physical activity had reduced risk of cardiovascular events compared with patients with reduced physical activity…. Leisure-time physical activity (LTPA) and exercise training are essential parts of current guidelines for patients with coronary artery disease (CAD). However, the contributions of LTPA and …
Read More »One-Third of Children in England Overweight/Obese but Trend Is Slowing
The leveling off of rates may indicate that public health campaigns are actually starting to work… A third of children in England are overweight/obese, finds a 20-year King’s College London study of electronic health records. But the rapid rise in prevalence may be starting to level off — at least …
Read More »Vegetarian Diets Cause Weight Loss Without Counting Calories and Exercise
The average person making the diet switch loses about 10 pounds according to a new meta-analysis of 15 studies… However, the review found that people who were heavier to start with lost more weight. Greater weight loss is reported among men and among older participants. Researchers with the nonprofit Physicians …
Read More »Lung Cancer Risk Reduction Seen in Nonsmokers on Metformin
But smokers taking the drug may have slightly increased risk…. Diabetic nonsmokers who had taken metformin had a decreased risk of lung cancer compared with metformin non-users, researchers said. A retrospective analysis covering 47,351 diabetic patients 40 and older found that, while metformin use was not associated with lower lung …
Read More »How Long Should the Antibiotic Therapy for Nonsurgically Treated Diabetic Foot Osteomyelitis Be?
Six weeks may be just enough…. Little is known about the optimal duration of antibiotic therapy for diabetic foot osteomyelitis (DFO). French researchers compared the effectiveness of 6 versus 12 weeks of antibiotic therapy in patients with DFO treated nonsurgically (i.e., antibiotics alone). This was a prospective randomized trial comparing …
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