A new combination of two FDA-approved drugs has shown a remarkable 8.7% average weight loss and a reduction of 1 point for A1c in just 12 weeks…

Glargine 300 more effective than glargine 100 currently available… Two single-dose studies were conducted in Japan and Europe to compare the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of new insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) in people with type 1 diabetes mellitus. In two double-blind, randomized, crossover …

The GLP-1 agonist albiglutide was added to the regimen of patients already on metformin and glimepiride…

But the effects are modest and type 2 patients on metformin can do moderate exercise without undue fear of hypoglycemia… Before, during, and after a 45-min bout of exercise at 60% VO2max, glucose kinetics were determined by isotope tracer technique in patients with type 2 diabetes mellitus with metformin treatment …

Can metformin reduce the risk of cancer for those with type 2 diabetes?… In previous studies, metformin has been shown to decrease the risk of cancer in type 2 diabetes. A recent meta-analysis showed a 34% reduction in the incidence of any cancer and a 33% reduction in cancer mortality; …

Muscle quality is also better with good control but muscle mass did not show any significant effect from higher HbA1c’s in the study.…

Insulin resistance with increasing LDL cholesterol were related to low peak volume of oxygen level… Diabetic nephropathy and cardiovascular disease are strongly related in adults with type 1 diabetes, yet little is known about this relationship in adolescents prior to the onset of detectable clinical disease. The researchers hypothesized that …

Urinary creatinine could reveal the relationship between muscle quality and actual muscle mass…

The women also experienced reduced beta cell function…. Researchers from the University of Southern California, Los Angeles, assessed associations between dietary intake and rates of change in insulin resistance and β-cell function in Hispanic women with prior gestational diabetes mellitus (GDM). Sixty-two nondiabetic Hispanic women with pregnancies complicated by GDM …

Diabetic patients can lose weight with medication specific for weight loss... In two randomized, double-blind and placebo-controlled studies, the safety and efficacy of treatment with phentermine (PHEN) and topiramate ER (TPM ER) (Qsymia) plus lifestyle for weight loss and glycemic benefits were measured. The studies included obese/overweight adults with type 2 diabetes. …