About 11,000 patients using both insulin and sulfonylurea were evaluated… Ulrik M. Mogensen, MD, of the department of cardiology at University Hospital Rigshospitalet in Denmark, and colleagues evaluated patients receiving sulfonylurea with insulin and 16,910 patients receiving metformin with insulin to determine the differences in outcomes of treatment combinations. Outcome …

According to consensus guidelines, relieving pressure on the foot through the use of off-loading improves healing outcomes and reduces complications in patients with diabetic foot ulcers… “The Management of Diabetic Foot Ulcers Through Optimal Off-Loading – Building Consensus Guidelines and Practical Recommendations to Improve Outcomes,” was authored by a multidisciplinary …

The investigational SGLT2 inhibitor remogliflozin showed benefits for glucose lowering in type 2 diabetes…

Improved glycemic control can reduce A1c, medical costs and complications… According to a new study, early introduction of insulin could save money, help more patients reach A1c goals and decrease diabetes-related complications and mortality. Currently, insulin therapy for persons with type 2 diabetes is traditionally added to an anti-hyperglycemic regimen …

A new study has identified the mechanisms that turn white fat into healthier brown fat…

Evidence suggests that the timing of diabetes onset and exposure to serious hypoglycemia may be factors in the cognitive decline of type 1 diabetics… The new study is the first of its kind to follow intelligence quotient (IQ) in type 1 diabetes patients from diagnosis in childhood into young adulthood …

The U.S. Food and Drug Administration has approved Saxenda as a treatment option for chronic weight management in addition to a reduced-calorie diet and physical activity….

Interoperability protocols unveiled for diabetes technologies… The communication protocols define how diabetes devices such as insulin pumps, blood glucose meters, and continuous glucose monitors talk with each other and with other devices such as smart phones and computers. They were developed jointly by JDRF and the Center for Global eHealth …

FDA Approves Liraglutide (Saxenda) for Weight Loss The U.S. Food and Drug Administration has approved Saxenda (liraglutide [rDNA origin] injection) as a treatment option for chronic weight management in addition to a reduced-calorie diet and physical activity. See this week’s Item 11. "The approval of Saxenda adds a unique tool …

  The first insulin/incretin mimetic combination launched overseas, Xultophy is a prefilled pen containing a fixed-ratio combination of insulin degludec and liraglutide, licensed in Europe for the treatment of type 2 diabetes in combination with oral hypoglycemics. Xultophy is the first product to combine a basal insulin and an incretin mimetic …