In this week’s Homerun Slides, Dr. Stanley Schwartz reviews pioglitazone as a therapy for both diabetes and cardiovascular issues. Topics include: Pioglitazone in Dysmetabolic Syndrome, Prediabetes, Type 2 Diabetes; Effect of Pioglitazone on Cardiac Mass and Function: and Glitazones (including rosiglitazone) and Cardiac Function…. To download these slides in PowerPoint (.ppt) format, …

It appears that the weather this winter may turn out to be worse than last year’s. Even here in sunny St. Petersburg, Fla., I had to pull out the winter gear for cycling. During these cold times patients often complain about their feet hurting more than usual. This could be …

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP The high-risk diabetic foot The lifetime risk of a person with diabetes developing foot ulceration is around 25%. Recent studies suggest that the population-based incidence of diabetic foot ulcers is 1-4% with a prevalence of 4-10%. The risk of amputation is 10–30-fold …

Targeting inflammation and fibrosis in the small blood vessels of the pancreatic islets may offer a new way of treatment….

There is some level of risk of CVD events that would result in a positive trade-off of benefit and risk for the use of aspirin, but the precise level of risk is remains uncertain….

Participants performed significantly worse on the working memory tasks…. Type 2 diabetes can be associated with cognitive impairment and the risk of Alzheimer’s disease. No studies have yet shown how type 2 diabetes affects working memory task and is related to brain function. The study used participants from the Beijing …

Liraglutide can preserve beta cell function over 48 weeks following initial elimination of glucotoxicity….

Offspring count higher for unaffected siblings, adult-onset type 1 patients…. The Finnish researchers assessed fertility, defined as number of offspring, in the affected and unaffected siblings included in the T1DGC. Clinical information was collected from participants aged ≥18 years at the time of examination. The number of offspring of affected …

Meta-analysis shows some reduction in HbA1c but not a significant change in fasting glucose…. Previous studies have shown a possible association between vegetarian diets and lower rates of type 2 diabetes. Studies have also shown improved glycemic control when subjects were switched from an omnivorous diet to a vegetarian diet. …

Degree of glycemic control is investigated for excess risk of death due to cardiovascular cause…. When compared to the general population, patients with type 1 diabetes are at increased risk of premature death. The most common cause of death is cardiovascular disease in patients over thirty years of age. Adequate …