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Monthly Archives: October 2014

Wider Diabetes Screening Needed

Draft recommendations from the USPSTF call for diabetes and blood glucose screening for people 45 and older and younger adults with risk factors. The guidelines, updated from 2008, are similar to those made by other medical groups and include recommendations for diet and exercise interventions for at-risk patients. The new …

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Interventions to Prevent Development of Diabetes

As diabetes develops, we currently waste the first ∼10 years of the natural history. If we found prediabetes and early diabetes when they first presented and treated them more effectively, we could prevent or delay the progression of hyperglycemia and the development of complications. Evidence for this comes from trials …

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Egg-rich Diet Safe for Diabetes Patients

Type 2 diabetes patients who followed an egg-rich diet did not show worse lipid levels than those who had lower egg consumption, according to research presented at the EASD meeting. Data also showed that an egg-rich diet was tied to better appetite control and satiety at three months. The study …

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GLP-1 Receptor Agonist a Treatment Option in Type 2 Patients with Renal Insufficiency

Phase 3 trial demonstrates the safety and efficacy of albiglutide in type 2 diabetes patients with renal impairment…. Renal impairment is a common comorbid condition in type 2 diabetes patients with reported incidence rates as high as 35%. Those with renal insufficiency often find their diabetes treatment options limited. Possible …

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New GLP-1 Receptor Agonist as an Alternative to Insulin Glargine?

Dulaglutide shows efficacy in diabetes patients with poor glycemic control already taking multiple oral medications…. Patients with uncontrolled diabetes already taking multiple oral agents often require insulin therapy for better glycemic control but insulin therapy is associated with hypoglycemia and weight gain. Dulaglutide, approved by the FDA in September 2014, …

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Two Positive Phase 3 Trials for ITCA 650, a GLP-1 Agonist, in Type 2 Diabetes

FREEDOM-1 and FREEDOM-1 High Baseline (HBL) study showed positive results when the continuous subcutaneous infusion of exenatide is added to standard oral diabetes medications….  ITCA 650 is a continuous subcutaneous infusion of exenatide through a pump for the treatment of type 2 diabetes. FREEDOM-1 is a double blinded, randomized, placebo-controlled, multicenter, phase …

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