ITCA 650 A 1 year implant dose of exenatide in type 2 diabetes shows positive results. See item #6 for more information. See more GLP-1 Agonist Resources
Read More »Monthly Archives: October 2014
Wider Diabetes Screening Needed
Draft recommendations from the USPSTF call for diabetes and blood glucose screening for people 45 and older and younger adults with risk factors. The guidelines, updated from 2008, are similar to those made by other medical groups and include recommendations for diet and exercise interventions for at-risk patients. The new …
Read More »Interventions to Prevent Development of Diabetes
As diabetes develops, we currently waste the first ∼10 years of the natural history. If we found prediabetes and early diabetes when they first presented and treated them more effectively, we could prevent or delay the progression of hyperglycemia and the development of complications. Evidence for this comes from trials …
Read More »Egg-rich Diet Safe for Diabetes Patients
Type 2 diabetes patients who followed an egg-rich diet did not show worse lipid levels than those who had lower egg consumption, according to research presented at the EASD meeting. Data also showed that an egg-rich diet was tied to better appetite control and satiety at three months. The study …
Read More »Non-Caloric Artificial Sweeteners May Induce Glucose Intolerance
Consumption of non-caloric artificial sweeteners seems to induce glucose intolerance in mice and humans by altering gut microbiota….
Read More »HbA1c Testing Frequency Matters
Quarterly HbA1c testing associated with better glycemic control….
Read More »GLP-1 Receptor Agonist a Treatment Option in Type 2 Patients with Renal Insufficiency
Phase 3 trial demonstrates the safety and efficacy of albiglutide in type 2 diabetes patients with renal impairment…. Renal impairment is a common comorbid condition in type 2 diabetes patients with reported incidence rates as high as 35%. Those with renal insufficiency often find their diabetes treatment options limited. Possible …
Read More »Low Carb Diet Improves Quality of Life for Type 2 Diabetes Patients
Type 2 diabetes patients on a low-carb diet had improvements in physical function, pain reduction, and overall health after 12 months….
Read More »New GLP-1 Receptor Agonist as an Alternative to Insulin Glargine?
Dulaglutide shows efficacy in diabetes patients with poor glycemic control already taking multiple oral medications…. Patients with uncontrolled diabetes already taking multiple oral agents often require insulin therapy for better glycemic control but insulin therapy is associated with hypoglycemia and weight gain. Dulaglutide, approved by the FDA in September 2014, …
Read More »Two Positive Phase 3 Trials for ITCA 650, a GLP-1 Agonist, in Type 2 Diabetes
FREEDOM-1 and FREEDOM-1 High Baseline (HBL) study showed positive results when the continuous subcutaneous infusion of exenatide is added to standard oral diabetes medications…. ITCA 650 is a continuous subcutaneous infusion of exenatide through a pump for the treatment of type 2 diabetes. FREEDOM-1 is a double blinded, randomized, placebo-controlled, multicenter, phase …
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