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Monthly Archives: March 2014

FDA Puts Empagliflozin on Hold

Quality issues in the manufacturing plant prevents final approval…. The investigational type 2 diabetes drug empagliflozin won’t win the FDA’s approval until “previously observed deficiencies” at a manufacturing plant are fixed, the drug’s sponsors said last week. Eli Lilly and Boehringer Ingelheim said the FDA had issued a complete response …

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Letter from the Editor #719

We often talk about the increase in AGEs (Advanced Glycation Endproducts) in patients with diabetes. We mainly think about these AGE’s in the development of vascular injury in our diabetes patients. However, the collagen in our joints is also subject to glycosylation and this means that many of our diabetes …

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