Linagliptin, a DPP-4 inhibitor currently under clinical development for type 2 diabetes, produced “meaningful” reductions in blood sugar, according to results of a late-stage clinical study. The results of a 24-week, open-label arm of a phase-3 study of the investigational drug linagliptin combined with the generic drug metformin, were announced …
Read More »Yearly Archives: 2011
SGLT2 Inhibitor Updates
In the latest results, dapagliflozin improved control when glimepiride was added. Through 48 weeks, dapagliflozin plus glimepiride reduced HbA1c levels by 0.37% to 0.70% compared with placebo plus glimepiride. There were also sustained reductions in fasting plasma glucose and post-prandial glucose and small reductions in total body weight (1.3 to …
Read More »Eating Out Twice a Week Increases Risk of Diabetes
Two take-outs a week are enough to increase the risk of diabetes and heart disease, research shows. Young adults were more likely to have hidden health problems if they treated themselves to fast food on a twice-weekly basis, the study found. Additionally, women appear to be more susceptible to the …
Read More »Ninety-two Percent of Obese Kids Have a Vitamin D Deficiency
Overweight kids have lower levels of vitamin D than their slimmer counterparts, regardless of season, sex, or race and ethnicity.…
Read More »Low Carbs for Just Two Days a Week Spurs Weight Loss
Adhering to a strict, low-carbohydrate diet two days per week led to greater reductions in weight and insulin levels when compared with standard daily dieting.…
Read More »Flight and Fight Can Be Key to Weight Loss
Patients’ activity in the sympathetic nervous system that controls the fight or flight response appears to predict how well they will do when trying to lose weight….
Read More »Less than a Minute a Day ‘Keeps Diabetes Away’
Performing short cycle sprints three times a week could be enough to prevent and possibly treat type 2 diabetes.…
Read More »The Final Word on Chocolate Intake and Benefits to the Heart and Brain
A study by Buitrago-Lopez and colleagues found that daily chocolate consumption had a positive effect on cardiovascular risk factors.…
Read More »Strict Glycemic Control May Not Help Kidney Patients
Both tight glycemic control and poor glycemic control are associated with worse outcomes in diabetes patients with chronic kidney disease.…
Read More »Glycemic Control Linked to Brain Function and Structure
An accelerated decline in brain function is an important risk that needs to be examined further in relation to glycemic control in older people with long-standing diabetes.…
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