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390 Drugs That Can Affect Blood Glucose Levels

Knowing the drugs that can affect blood glucose levels is essential in properly caring for your diabetes patients. Some medicines raise blood sugar in patients while others might lower their levels. However, not all drugs affect patients the same way.

390 Drugs that Can Affect Blood Glucose Levels is also available for purchase in ebook format.

390 Drugs that can affect blood glucose Level

 

Last Revised: 03/1/2017

 

Table of Contents:

Drugs that May Cause Hyperglycemia

Drugs that May Cause Hypoglycemia

Drugs that May Cause Hyper- or Hypoglycemia

Drugs that Mask Hypoglycemia

 

Drugs That May Cause Hyperglycemia (High Blood Sugar)

(GENERIC NAME  |  BRAND NAME)

Abacavir  |  (Ziagen®)

Abacavir + lamivudine,zidovudine  |  (Trizivir®)

Abacavir + dolutegravir + lamivudine  |  (Triumeq®)

Abiraterone  |  (Zytiga®)

Acetazolamide  |  (Diamox®)

Acitretin  |  (Soriatane®)

Aletinib  |  (Alecensa®)

Albuterol  |  (Ventolin®, Proventil®)

Albuterol + ipratropium  |  (Combivent®)

Aliskiren + amlodipine + hydrochlorothiazide  |  (Amturnide®)

Aliskiren + amlodipine  |  (Tekamlo®)

Ammonium chloride

Amphotericin B  |  (Amphocin®, Fungizone®)

Amphotericin B lipid formulations IV  |  (Abelcet®)

Amprenavir  |  (Agenerase®)

Anidulafungin  |  (Eraxis®)

Aripiprazole  |  (Abilify®)

Arsenic trioxide  |  (Trisenox®)

Asparaginase  |  (Elspar®, Erwinaze®)

Atazanavir  |  (Reyataz ®)

Atazanavir + cobistat  |  (Evotaz®)

Atenolol + chlorthalidone  |  (Tenoretic®)

Atorvastatin  |  (Lipitor®)

Atovaquone  |  (Mepron®)

Baclofen  |  (Lioresal®)

Belatacept  |  (Nulojix®)

Benazepril + hydrochlorothiazide  |  (Lotension®)

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Betamethasone topical  |  (Alphatrex®, Betatrex®, Beta-Val®, Diprolene®, Diprolene® AF, Diprolene® Lotion, Luxiq®, Maxivate®)

Betamethasone +clotrimazole  |  (Lotrisone® topical)

Betaxolol Betoptic® eyedrops,  |  (Kerlone® oral)

Bexarotene  |  (Targretin®)

Bicalutamide  |  (Casodex®)

Bisoprolol + hydrochlorothiazide  |  (Ziac®)

Brentuximab vedotin  |  (Adcetris®)

Budesonide  |  (Uceris®)

Bumetanide  |  (Bumex®)

Cabozantinib  |  (Cabometyx®)

Caffeine  |  (Caffeine in moderation may actually be beneficial in diabetes but in large amounts can raise blood sugar.)

Calcipotriene + betamethasone  |  (Enstillar®)

Candesartan + hydrochlorothiazide  |  (Atacand HCT®)

Captopril + hydrochlorothiazide  |  (Capozide®)

Carfilzomib  |  (Kyprolis®)

Carteolol  |  (Cartrol® oral, Occupress® eyedrops)

Carvedilol  |  (Coreg®)

Ceftaroline  |  (Teflaro®)

Ceftozolane + tazobactam  |  (Zerbaxa)

Chlorothiazide  |  (Diuril®)

Chlorthalidone  |  (Chlorthalidone Tablets®, Clorpres®, Tenoretic®, Thalitone®)

Choline salicylate  |  (Numerous tradenames of aspirin formulations; check label)

Choline salicylate + magnesium salicylate  |  (CMT®, Tricosal®, Trilisate®)

Clobetasol  |  (Clobevate®, Cormax®, Cormax® Scalp Application, Embeline® E, Olux®, Temovate®, Temovate® E, Temovate® Scalp Application)

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Clozapine  |  (Clozaril®, FazaClo®)

Conjugated estrogens  |  (Estrace®, Estring®, Femring®, Premarin®, Vagifem®, Cenestin®, Enjuvia®, Estrace®, Femtrace®, Gynodiol®, Menest®, Ogen®)

Conjugated estrogens + bazedoxifene  |  (Duavee®)

Conjugated estrogens + medroxyprogesterone  |  (Premphase®, Prempro®)

Corticosteroids  |  (Numerous tradenames; check label)

Corticotropin

Cortisone  |  (Numerous tradenames; check label)

Cyclosporine  |  (Sandimmune®, Neoral®, Gengraf®)

Dabrafenib  |  (Tafiniar®)

Daclizumab  |  (Zenapax®)

Darunavir + cobistat  |  (Prezcobix®)

Decitabine  |  (Dacogen®)

Desonide  |  (DesOwen®, Tridesilon®)

Desoximetasone  |  (Topicort®)

Dexamethasone  |  (Adrenocot®, Dalalone®, Decadron®, Decaject®, Dekasol®, Dexacort®, Dexasone®, Dexim®, Dexone®,Hexadrol®, Medidex®, Primethasone®, Solurex®, Dexamethasone Intensol®)

Dextromethorphan + promethazine  |  (Phenergan® with Dextromethorphan, Phen- TussDM®)

Diazoxide  |  (Proglycem®)

Dinutuximab  |  (Unituxin®)

Dolutegravir  |  (Tivicay®)

Empagliflozin + metformin  |  (Synjardy®)

Enalapril + hydrochlorothiazide  |  (Vaseretic®)

Encainide  |  (Enkaid®)

Ephedrine and Guaifenesin  |  (Primatene ® tablets, otc – this medication includes ephedrine and guaifenesin. Guaifenesin is not responsible for hyperglycemia )

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Epinephrine   |  (EpiPen ®, EpiPen® Jr, Primatene® Mist, otc)

Esterified estrogens, estrone, estropipate

Esterified estrogens + methyltestosterone  |  (Estratest®)

Estradiol, ethinyl estradiol  |  (Alora®, Climara®, Congest®, Delestrogen®, Depo-Estradiol®, Depogen®, Estinyl®, Estrace®, Estraderm®, Estragyn 5®, Estragyn LA 5®, Estrasorb®, EstroGel®, Estro-L.A.®, Gynodiol®, Kestrone-

5®, Neo-Estrone®, Menest®, Menostar®, Ogen .625®, Ogen®, Ortho-Est®, Premarin®, Valergen®, Vivelle®, Vivelle-Dot®)

Estradiol + norethindrone  |  (Activella®)

Estradiol + norgestimate  |  (Prefest®)

Estramustine  |  (Emcyt®)

Ethacrynic acid  |  (Edecrin®, Sodium Edecrin®)

Everolimus  |  (Afinitor®, Zortress®)

Everolimus  |  (Zortress®)

Ezetimibe, Atorvastatin  |  (Liptruzet®)

Fidaxomicin  |  (Dificid®)

Fluticasone  |  (Arnuity Ellipta®)

Fluticasone + vilanterol  |  (Breo Elipta®)

Fluticasone/Salmeterol  |  (Airduo Respiclick®)

Fluoxetine  |  (Prozac®, Sarafem®)

Flurandrenolide  |  (Cordran®, Cordran® SP, Cordran® Tape)

Formoterol  |  (Foradil® Aerolizer® Inhaler)

Fosamprenavir  |  (Lexiva ®)

Fosinopril + hydrochlorothiazide  |  (Monopril HCT®)

Furosemide  |  (Lasix®)

Gabapentin  |  (Gralise®, Horizant®)

Gemtuzumab ozogamicin  |  (Mylotarg®)

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Glucosamine  |  (Possible increase in insulin resistance; more likely with intravenous use)

Glycopyrrolate  |  (Cuvposa®)

Glycopyrrolate/Formoterol  |  (Bevespi Aerosphere®)

Hydrochlorothiazide  |  (Aldactazide®, Aldoril®, Capozide®, Dyazide®, HydroDIURIL®, Inderide®, Lopressor® HCT, Maxzide®,Microzide®, Moduretic®, Timolide®, Vaseretic®)

Hydrochlorothiazide + irbesartan  |  (Avalide®)

Hydrochlorothiazide + lisinopril  |  (Prinzide®, Zestoretic®)

Hydrochlorothiazide + losartan  |  (Hyzaar®)

Hydrochlorothiazide + metoprolol  |  (Lopressor HCT®)

Hydrochlorothiazide + moexipril  |  (Uniretic®)

Hydrochlorothiazide + quinapril  |  (Accuretic®, Quinaretic®)

Hydrochlorothiazide + telmisartan  |  (Micardis HCT®)

Hydrochlorothiazide + valsartan  |  (Diovan HCT®)

Hydrocortisone  |  (Numerous trade names of topical hydrocortisone formulations; check label)

Indacaterol  |  (Arcapta®)

Indapamide  |  (Lozol®)

Indinavir  |  (Crixivan®)

Interferon alfa-2a  |  (Roferon-A®)

Interferon alfa-2b  |  (Intron-A®)

Interferon alfa-2b + ribavirin  |  (Rebetron®)

Interferon alfa-n1  |  (Alferon-N®)

Irinotecan  |  (Camptosar®)

Isoniazid  |  (Laniazid®, Nydrazid®)

Isotretinoin  |  (Accutane®)

Liothyronine  |  (Cytomel®)

Lamivudine  |  (Epivir®, Epivir-HBV®)

Levalbuterol  |  (Xoponex®, Xopenex HFA®)

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Levonorgestrel  |  (Plan B®, Norplant System®)

Levothyroxine  |  (Synthroid®, Levoxyl®, Tirosint-Sol®)

Lopinavir + ritonavir  |  (Kaletra®)

Lucinactant  |  (Surfaxin®)

Lurasidone  |  (Latuda®)

Magnesium salicylate  |  (Bayer Select® Backache Pain Formula, Doans® Pills, Mobidin®, Nuprin® Backache Caplet)

Medroxyprogesterone  |  (Provera®, Depo-Provera®)

Megestrol  |  (Megace®)

Methylprednisolone  |  (A-methaPred®, ADD-Vantage®, Depo-Medrol®, Medrol®,
Medrol® Dosepak, Meprolone® Unipak, Solu-Medrol®)

Metolazone  |  (Zaroxolyn®, Mykrox®)

Metoprolol  |  (Lopressor®, Lopressor® HCT, Toprol XL®)

Modafinil  |  (Provigil®)

Momentasone furoate + formoterol fumarate dihydrate  |  (Dulera®)

Moxifloxacin  |  (Avelox®, Avelox® I.V.)

Mycophenolate  |  (CellCept®)

Nadolol  |  (Corgard®)

Nelfinavir  |  (Viracept®)

Netupitant + palonosetron  |  (Akynzo®)

Niacin, niacinamide  |  (Niacor®, Niaspan®, Nicolar®, Nicotinex®, Slo-Niacin®)

Nilotinib  |  (Tasigna®)

Nilutamide  |  (Nilandron®)

Nitric oxide  |  (INOmax®)

Nivolumab  |  (Opdivo®)

Norethindrone  |  (Aygestin®, Nor-QD®, Micronor®)

Norgestrel  |  (Orvette®)

Nystatin  |  (Mycostatin®, Nystat-Rx®, Nystop®, Pedi-Dri®)

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Nystatin + triamcinolone  |  (Dermacomb®, Myco II®, Mycobiotic II®, Mycogen II®,
Mycolog II®, Myco-Triacet II®, Mykacet®, Mykacet II®, Mytrex®, Tristatin II®)

Octreotide  |  (Sandostatin®, Sandostatin LAR®)

Olanzapine  |  (Zyprexa®)

Olaparib  |  (Lynparza®)

Olaratumab  |  (Lartruvo®)

Olmesartan + amlodipine + hydrochlorothiazide  |  (Tribenzor®)

Oxybutynin  |  (Anturol®)

Oxycodone  |  (Oxecta®, Xtampza ER®)

Panobinostat  |  (Farydak®)

Pantoprazole  |  (Protonix®, Protonix® I.V.)

Pegaspargase  |  (Oncaspar®)

Peginterferon alfa-2b  |  (PEG-Intron®, Sylatron®)

Pembrolizumab  |  (Keytrenda®)

Pentamidine  |  (Pentam 300®)

Peramivir  |  (Rapivab®)

Perindopril + amlodipine  |  (Prestalia®)

Phenylephrine*  |  (Sudafed PE®, and others)

Phenytoin  |  (Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Phenytek®)

Pomalidomide  |  (Pomalyst®)

Prednisolone  |  (AK-Pred®,Blephamide®,Blephamide®,Liquifilm®,Econopred® Plus, Inflamase® Forte, Inflamase® Mild, Poly-Pred® Liquifilm®, Pred Forte®, Pred Mild®, Pred-G®, Pred-G® Liquifilm®, Delta Cortef®,Pediapred®,Prelone®)

Prednisone  |  (Prednisone Intensol®, Sterapred®, Sterapred® DS, Rayos DR®)

Progesterone  |  (Prometrium®)

Pseudoephedrine*  |  (Claritin D®, Sudafed®, and others)

* There are many other OTC and prescription medications that contain pseudoephedrine and phenylephrine.

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Quetiapine  |  (Seroquel®)

Risperidone  |  (Risperdal®, Risperdal® M-TAB®)

Ritodrine  |  (Yutopar®)

Ritonavir  |  (Norvir®)

Rituximab  |  (Rituxan®)

Salmeterol  |  (Serevent®, Serevent® Diskus®)

Salsalate  |  (Argesic®-SA, Disalcid®, Mono-Gesic®, Salflex®, Salsitab®)

Saquinavir  |  (Invirase®)

Sodium oxybate  |  (Xyrem®)

Somatropin  |  (Genotropin®, Genotropin Miniquick®, Humatrope®,Norditropin artridges®,Norditropin NordiFlex®,Nutropin®, Nutropin AQ®, Saizen®, Serostim®, Zorbtive®)

Sonidegib  |  (Odomzo®)

Sotalol  |  (Betapace®, Betapace AF®, Sorine®)

Streptozocin  |  (Zanosar®)

Tacrolimus  |  (Prograf®, Protopic®)

Temsirolimus  |  (Torisel®)

Tesamorelin  |  (Egrifta®)

Thyroid  |  (Armour Thyroid®, Naturethroid®)

Tiotropium + Olodaterol  |  (Stiolto Respimat®)

Tipranavir  |  (Aptivus®)

Tolvaptan  |  (Samsca®)

Torsemide  |  (Demadex®, Demadex Oral®)

Trametinib  |  (Mekinist®)

Triamcinolone  |  (Aristocort®, Aristospan®, Asthmacort®, Flutex®, Kenalog®, Tac®, Triacet®)

Umeclidium + vilanterol  |  (Anoro Ellipta®)

Ursodeoxycholic acid, ursodiol  |  (Actigall®, Urso®)


 

Drugs That May Cause Hyperglycemia (High Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Valproic acid, divalproex sodium  |  (Depacon®, Depakene®, Depakene® Syrup, Depakote®, Depakote® ER,Depakote® Sprinkle)

Vitamin C  |  (Ascorbic acid, Ascorbate)

Vitamin E  |  (Tocopherol, Tocotrienol)

Ziprasidone  |  (Geodone®)

Zolpidem  |  (Intermezzo®)

 

 

Drugs That May Cause Hypoglycemia (Low Blood Sugar)

(GENERIC NAME  |  BRAND NAME)

Abliglutide  |  (Tanzeum®)

Acebutolol  |  (Sectral®)

Acetohexamide  |  (Dymelor®)

Albiglutide  |  (Tanzeum®)

Alcohol

Aloe – Oral Herbal Supplement, especially if taken with other agents such as glyburide, glipizide, nateglinide, repaglinide, glimepiride, or insulin.

Alogliptin  |  (Nesina®)

Alogliptin/pioglitazone  |  (Oseni®)

Alogliptin/metformin  |  (Kazano®)

Amphotericin B  |  (Ambisome®, Amphocin®, Fungizone Intravenous® Amphotec®, Abelcet®)

Amphotericin B lipid formulations  |  (Abelcet®, AmBisome®)

Aripiprazole  |  (Aristada®)

Asian Ginseng  |  (Ginseng; Panax ginseng)

Aspirin  |  (Numerous tradenames; check label)

Aspirin + dipyridamole  |  (Aggrenox®)

Atenolol  |  (Tenormin®, Tenoretic® containing atenolol & chlorthalidone)

Betaxolol  |  (Betoptic®, Betoptic S® eyedrops, Kerlone® oral)

Bisoprolol  |  (Zebeta®)

Bisoprolol + hydrochlorothiazide  |  (Ziac®)

Brexpiprazole  |  (Rexulti®)

Bromocriptine  |  (Cycloset®)

Canagliflozin  |  (Invokana®)

Canagliflozin + metformin  |  (Invokamet®)

Canagliflozin/Metformin  |  (Invokamet XR®)

Chloramphenicol  |  (Chloromycetin®)

Chlorpropamide  |  (Diabinese®)

Drugs That May Cause Hypoglycemia (Low Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Choline salicylate  |  (Acuprin 81®, Amigesic®, Anacin Caplets®, Anacin Maximum Strength®, Anacin Tablets®, Anaflex 750® Arthritis Pain, Ascriptin® Arthritis Pain)

Choline salicylate + magnesium salicylate C  |  (MT®, Tricosal®, Trilisate®)

Chromium  |  (Various tradenames; check label)

Clarithromycin B  |  (Biaxin® Filmtab®, Biaxin® Granules, Biaxin® XL, Filmtab,
Biaxin® XL Pac, Prevpac®)

Dalbavancin  |  (Dalvance®)

Dapagliflozin  |  (Farxiga®)

Dapagliflozin + Metformin  |  (Xigduo XR®)

Diazoxide  |  (Proglycem®)

Dicumarol  |  (Coumadin®, Miradon®)

Diltiazem  |  (Cardizem®, Tiazac®)

Disopyramide  |  (Norpace®, Norpace® CR)

Dorzolamide + timolol  |  (Cosopt®)

Doxepin  |  (Silenor®)

Dulaglutide  |  (Trulicity®)

Empagliflozin  |  (Jardiance®)

Empagliflozin/linagliptin  |  (Glyxambi®)

Empagliflozin/Metformin  |  (Synjardy XR®)

Ertugliflozin  |  (Not FDA approved- Phase III clinical trials)

Etanercept-szzs (Erelzi®)

Exenatide  |  (Byetta®, Bydureon®)

Fluoxetine  |  (Prozac®, Sarafem®)

Fosphenytoin  |  (Cerebyx®, Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Mesantoin®, Peganone®,Phenytek®)

Glimepiride  |  (Amaryl®)

Glimepiride and Rosiglitazone  |  (Avandaryl®)

Drugs That May Cause Hypoglycemia (Low Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Glipizide  |  (Glucotrol®, Glucotrol XL®)

Glipizide and Metformin  |  (Metaglip®)

Glucagon  |  (GlucaGen®)

Glyburide  |  (Diabeta®, Glynase®, Micronase®,Glycron®)

Glyburide + metformin  |  (Glucovance®)

Horse chestnut  |  (Aesculus hippocastanum)

Hydrochlorothiazide + metoprolol  |  (Lopressor HCT®)

Insulin  |  (Lantus®, Levemir®, NPH®, Humulin®, Novolin®, Apidra®, Novolog®, Humalog®, Tresiba®, Afrezza®- inhaled, Abasaglar®, Ryzodeg®, Xultophy®- not FDA approved, Toujeo®, Locemia®- not FDA approved, V-go®)

Interferon beta-1b  |  (Betaseron®)

Isavuconazonium  |  (Cresemba®)

ITCA 650®- Not FDA approved

Lenvatinib  |  (Lenvima®)

Levofloxacin  |  (Levaquin®, Levaquin® in Dextrose Injection Premix, Quixin®)

Liraglutide  |  (Victoza®, Saxenda®)

Linagliptin  |  (Tradjenta®)

Linagliptin + Metformin  |  (Jentadueto®, Jentadueto XR®)

Lixisenatide  |  (Adlyxin®, Lyxumia®- currently approved in Europe)

Lixisenatide/Glargine  |  (LixiLan®)- Not FDA approved

Locaserin  |  (Belviq®)

Magnesium salicylate  |  (Bayer Select® Backache Pain Formula, Doans® Pills, Mobidin®, Nuprin® Backache Caplet)

Metformin  |  (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, Riomet®)

Metreleptin  |  (Myalept®)

Metoprolol  |  (Lopressor®, Lopressor® HCT, Toprol XL®)

Metreleptin  |  (Myalept®)

Drugs That May Cause Hypoglycemia (Low Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Mifepristone  |  (Korlym®)

Morphine  |  (Kadian®, MS Contin®, MSIR®, Roxanol®)

Nadolol  |  (Corgard®)

Nateglinide  |  (Starlix®)

Nifedipine  |  (Adalat CC®, Procardia®, Afeditab ® CR)

Nivolumab  |  (Opdivo®)

Octreotide  |  (Sandostatin®, Sandostatin LAR® Depot)

Oritavacin  |  (Orbactiv®)

Paloperidone  |  (Invega®)

Penicillamine  |  (Cuprimine®, Depen®)

Pentamidine  |  (Nebupent®, Pentam 300®)

Phenelzine  |  (Nardil®)

Phenytoin  |  (Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Phenytek®)

Pindolol  |  (Visken®)

Pioglitazone  |  (Actos®) – |  ( hypoglycemia usually only when in combination with other diabetic drugs such as sulfonylureas or insulin)

Pioglitazone and Glimepiride  |  (Duetact®) – the glimepiride component of this drug gives it the possibility of causing hypoglycemia alone or in combination with other diabetes medicines. This is more likely to occur when one skips a regular meal or when unusual physical activities occur.

Pioglitazone and Metformin  |  (Actoplus Met®,ActoPlus Met XR®)

Pramlintide  |  (Symlin®)

Pregabalin  |  (Lyrica®)

Probenecid  |  (Benemid®, Probalan®)

Quinine  |  (Quinamm®, Quindan®, Quiphile®, Q-vel®, Strema®)

Quinupristin + dalfopristin  |  (Synercid®)

Repaglinide  |  (Prandin®)

Repaglinide and Metformin  |  (PrandiMet®)

Ritodrine  |  (Yutopar®)

Rituximab  |  (Rituxan®)

Drugs That May Cause Hypoglycemia (Low Blood Sugar) – Continued

(GENERIC NAME  |  BRAND NAME)

Rosiglitazone  |  (Avandia®)

Rosiglitazone and Metformin  |  (Avandamet®)

Rotigotine  |  (Neupro®)

Salicylates  |  (Numerous tradenames of aspirin formulations; check label)

Salsalate  |  (Argesic®-SA, Disalcid®, Mono-Gesic®, Salflex®,Salsitab®)

Saxagliptin  |  (Onglyza®)

Saxagliptin + metformin  |  (Kombiglyze XR®)

Selegiline  |  (Eldepryl®)

Semaglutide- Not FDA approved, phase III clinical trials

Sitagliptin  |  (Januvia®)

Sitagliptin and Metformin HCL  |  (Janumet®)

Sodium ferric gluconate complex  |  (Ferrlecit®)

Somatropin  |  (Genotropin®, Genotropin Miniquick®, Humatrope®, Norditropin cartridges®, Norditropin NordiFlex®, Nutropin, Nutropin AQ®, Saizen®, Serostim®, Zorbtive®)

Sotalol  |  (Betapace®, Betapace AF®, Sorine®)

Streptozocin  |  (Zanosar®)

Sulfadiazine  |  (Microsulfon®)

Tacrolimus P  |  (Prograf®, Protopic®)

Tetracaine  |  (Altacaine®, Tetcaine®, Pontocaine®)

Theophylline  |  (Theo-24®, Theo-Dur®, TheoCap®)

Timolol  |  (Timoptic®, Timoptic-XE®)

Tolazamide  |  (Tolinase®)

Tolbutamide  |  (Orinase®)

Tranylcypromine  |  (Parnate®)

Varenicline  |  (Chantix®)

Verapamil  |  (Calan®, Calan SR®, Isoptin SR®, Verelan®)

Amphotericin B  |  (Ambisome®, Amphocin®, Fungizone Intravenous® Amphotec®, Abelcet®)

Drugs that can cause Hyper or Hypoglycemia

(GENERIC NAME  |  BRAND NAME)

Amphotericin B lipid formulations  |  (Abelcet®, AmBisome®)

Aspirin/Omeprazole  |  (Yosprala®)

Avanafil  |  (Stendra®)

Axitinib  |  (Inlyta®)

Betaxolol Betoptic® eyedrops,  |  (KERLONE® oral)

Bisoprolol + hydrochlorothiazide  |  (Ziac®)

Choline salicylate  |  (Numerous tradenames of aspirin formulations; check label)

Choline salicylate + magnesium salicylate  |  (CMT®, Tricosal®, Trilisate®)

Ciprofloxacin  |  (Otiprio®)

Darunavir  |  (Prezista®)

Diazoxide  |  (Proglycem®)

Doxepin  |  (Silenor®)

Elvitegravir + cobicistat + emtricitabine + tenofovir  |  (Stribild®)

Emtricitabine + rilpivirine + tenofovir  |  (Complera®)

Fentanyl  |  (Abstral®, Lazanda®, Subsys®)

Fluoxetine  |  (Prozac®, Sarafem®)

Hydrochlorothiazide + metoprolol  |  (Lopressor HCT®)

Insulin degludec/Liraglutide  |  (Xultophy®)

Insulin glargine/Lixisenatide  |  (Soliqua®)

Ivacaftor  |  (Kalydeco®)

Lanreotide acetate  |  (Somatuline®)

Lenalidomide  |  (Revlimid®)

Lithium  |  (Eskalith®, Eskalith CR®, Lithobid®)

Magnesium salicylate  |  (Bayer Select® Backache Pain Formula, Doans® Pills, Mobidin®, Nuprin® Backache Caplet)

Mecasermin  |  (Increlex ®)

Mecasermin Rinfabate  |  (Iplex ®)

Drugs that can cause Hyper or Hypoglycemia – Continued

(GENERIC NAME  |  BRAND NAME)

Metoprolol  |  (Lopressor®, Lopressor® HCT, Toprol XL®)

Nadolol  |  (Corgard®)

Naproxen + esomeprazole  |  (Vimovo®)

Octreotide  |  (Sandostatin®, Sandostatin LAR® Depot)

Omacetaxine  |  (Synribo®)

Oxcarbazepine  |  (Oxtellar XR®)

Oxycodone + acetaminophen  |  (Xartemis®)

Pancrelipase  |  (Ultresa®, Viokace®)

Paroxetine  |  (Brisdelle®)

Pasireotide  |  (Signifor®)

Pazopanib  |  (Votrient ®)

Pentamidine  |  (Nebupent®, Pentam 300®)

Phenytoin  |  (Dilantin®, Dilantin-125®, Dilantin Infatabs®, Dilantin Kapseals®, Phenytek®)

Ponatinib

Rifampin  |  (Rifadin®, Rimactane®)

Ritodrine  |  (Yutopar®)

Rituximab  |  (Rituxan®)

Salsalate  |  (Argesic®-SA, Disalcid®, Mono-Gesic®, Salflex®,Salsitab®)

Sitagliptin + simvastatin  |  (Juvisync®)

Sunitinib  |  (Sutent®)

Somatropin  |  (Genotropin®, Genotropin Miniquick®, Humatrope®, Norditropin cartridges®, Norditropin NordiFlex®, Nutropin®, Nutropin AQ®, Saizen®, Serostim®, Zorbtive®)

Sotalol  |  (Betapace®, Betapace AF®, Sorine®)

Streptozocin  |  (Zanosar®)

Sunitinib  |  (Sutent®)

Pancrelipase  |  (Pancreaze®)

Pasireotide  |  (Signifor®)

Drugs that can cause Hyper or Hypoglycemia – Continued

(GENERIC NAME  |  BRAND NAME)

Pegloticase  |  (Krystexxa®)

Tacrolimus P  |  (Prograf®, Protopic®)

Testosterone gel  |  (Fortesta®)

Testosterone  |  (Aveed®, Natesto®, Vogelxo®)

Topiramate  |  (Qudexy®)

Vandetinib  |  (Vandetinib®)


Drugs that can MASK* Hypoglycemia

(GENERIC NAME  |  BRAND NAME)

Atenolol  |  (Tenormin®, Tenoretic® containing Atenolol & Chlorthalidone)

Carteolol  |  (Cartrol® oral, Occupress® eyedrops)

Carvedilol  |  (Coreg®, Coreg® Tiltabs®)

Clonidine  |  (Duraclon®, Catapres®, Catapres-TTS-1®, Catapres-TTS-2®, Catapres-TTS-3®)

Dronabinol |  (Syndros®)

Metoprolol  |  (Lopressor®, Lopressor® HCT, Toprol XL®)

Nadolol  |  (Corgard®)

Nebivolol  |  (Bystolic®)

Nebivolol/Valsartan  |  (Byvalson®)

Pindolol  |  (Visken®)

Propranolol, Propranolol Hydrochloride,  |  (Inderal®, Inderal LA®, Inderide®, Innopran® XL, Intensol®)

Timolol  |  (Timoptic®, Timoptic-XE®)
*          Recent research suggests that this may not occur.

 

Because of the constantly changing nature of the U.S. prescription and OTC drug marketplace, this list may not reflect the full range of drugs that may impact blood glucose levels. The information contained in this document is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over-the-counter drugs (including any herbal medicines or supplements) or following any treatment or regimen.

 

To check for updates to this list visit:

www.diabetesincontrol.com/drugs-that-can-affect-blood-glucose-levels/
References: