A few years back, I was working with an endocrinologist in St. Petersburg, managing his diabetes patients. We would get a lot of type 2 patients who had been started on basal insulin and then referred to us when their condition required the addition of mealtime insulin. Most of these …

Michael S. Irwig, MD, F.A.C.E., is board-certified in Endocrinology & Metabolism and is an associate professor of Medicine at The George Washington University School of Medicine & Health Sciences. He also is an adjunct associate professor of Medicine at Georgetown University School of Medicine.

In this week's Homerun Slides, we begin a new series showing the value of continuous glucose monitoring.

The effects are consistent with a role for O-GlcNAc in damping acute hormone- and phosphorylation-mediated signals in situations of chronic nutrient excess. Although discovered in the context of diabetes, the aforementioned changes mediated by the HBP can also be viewed as adaptive responses to excess nutrient flux: muscle cells protect themselves from excess glucose fluxes and the excess nutrients are eventually stored as fat. Indeed, if insulin signaling were not dampened and glycogen synthesis were effectively engaged even with overeating, a pound of ingested carbohydrate would result in approximately four pounds of hydrated glycogen in muscle, and it is easy to visualize diets rich in sodas and donuts resulting in the development of glycogen storage diseases.

In this Exclusive Interview transcript, Michael Irwig talks with Diabetes in Control publisher Steve Freed during the AACE 2018 convention in Boston about treating low testosterone and how diabetes and obesity can affect testosterone levels.

In this Exclusive Interview, Michael Irwig talks with Diabetes in Control publisher Steve Freed during the AACE 2018 convention in Boston about treating low testosterone.

In part 1 of this Exclusive Interview, Michael Irwig talks with Diabetes in Control Publisher Steve Freed about why men with diabetes typically have lower testosterone than men without diabetes.

In part 2 of this Exclusive Interview, Michael Irwig talks with Diabetes in Control Publisher Steve Freed about when to test for testosterone issues and the relationship between diabetes and sexual dysfunction.

In part 3 of this Exclusive Interview, Michael Irwig explains the variety of testosterone tests available in a discussion with Diabetes in Control Publisher Steve Freed.

In part 4 of this Exclusive Interview, Michael Irwig talks with Diabetes in Control Publisher Steve Freed about various testosterone products that are offered without prescription and best suggested treatments.