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Monthly Archives: March 2017

March 28, 2017

It seems that the do-all, fix-all, be-all for kidney problems is either an ARB or ACE-I. We start patients on these medications at the first sign of elevated glucose levels regardless of their blood pressure levels, as they “protect” the kidneys. This is definitely true, but what do we do …

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #68: Regulation of Glucose Metabolism in Liver Part 4 of 11

Gluconeogenic pathways: Gluconeogenesis is the synthesis of glucose from three carbon precursors such as alanine, pyruvate, lactate, and glycerol and is essentially a reversal of glycolysis. Under normal conditions, 90% of gluconeogenesis occurs in liver, and the rest occurs mainly in the renal cortex. Other sites of gluconeogenesis, such as the small intestine have been suggested but remain controversial.

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March 25, 2017

Most of the time when we speak about patients who are not diagnosed with diabetes and who develop complications, we are usually referring to vision changes or things like neuropathy. However, it now appears that there are a good number of these undiagnosed who die from ketoacidosis. This week, our …

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