Daily Archives: Sep 13, 2016

Sept. 13, 2016

Many publications take advantage of videos of Key Opinion Leaders in order to share information with their readers. Most of them will also convert the interview to a transcript. Most times a transcript is good when it is technical knowledge, but there are times when the information is more thought-provoking, …

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #41: Normal Beta-cell Function Part 6 of 6

Beta-Cell function and glucose homeostasis: Insulin secretion, together with the sensitivity to insulin of glucose-utilizing tissues, is a key player in glucose homeostasis. What is relevant for glucose homeostasis is not the absolute insulin secretion levels but insulin secretion relative to glucose, as typically assessed by the beta-cell dose-response during the physiologic condition of oral glucose ingestion. Thus, beta-cell glucose sensitivity is strongly inversely associated to mean glucose levels during a standard OGTT and explains, together with insulin sensitivity, a substantial proportion of the variability in glucose levels.

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