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Daily Archives: Mar 29, 2016

If you are old enough to remember the original Mission Impossible shows, then you probably remember the small cassette player that had a self-destructing tape that gave Mr. Phelps (played by Peter Graves) his mission. Each time, the show started with Phelps going to a private location and finding the tape …

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Don’t Blame All Symptoms on Glucose Levels

A woman, 72 years of age, type 2 diabetes, obesity, taking metformin, GLP1, ARB, and antidepressant (SSRI). Lost 20% total body weight in the past year. Recently complaining of dizziness and weakness. Glucose levels in the 60’s at home, at which time had symptoms of hypoglycemia. Glucose-lowering medications (metformin and GLP-1) were stopped. Continued to complain of dizziness and weakness especially in the morning.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #17: Development and Maintenance of the Islet Beta Cell Part 1 of 4

The discovery of insulin by Banting and Best in the early 1920s marked the beginning of a new era of diabetes research that focused on the study of insulin and the biology of the hormone-producing cells of the pancreas. In the ensuing decades, although much was learned regarding the synthesis, structure, and action of insulin, the developmental origins of insulin-producing β cells remained ambiguous.

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