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Which is Better? Insulin vs. Triple Oral Therapy for Newly Diagnosed Type 2 Diabetes

Which is Better? Insulin vs. Triple Oral Therapy for Newly Diagnosed Type 2 Diabetes: Early use of insulin after diagnosis of Type 2 diabetes is met with resistance because of associated weight gain, hypoglycemia, and fear of decreased compliance and quality of life (QoL). When compared with a clinically equivalent treatment regimen, insulin-based therapy is effective and did not cause greater weight gain or hypoglycemia nor decrease compliance, treatment satisfaction, or QoL. Insulin is safe, well-accepted, and effective for ongoing treatment of patients with newly diagnosed Type 2 diabetes. Diabetes Care. 2009;32(10):1789-1795