U-500 Insulin Pen "Coming Soon"
Because of the many errors reported when using U-500 insulin, Eli Lilly is developing a prefilled pen designed to deliver HUMULIN R U-500 (insulin human), and the company is also working with a development partner on the design of a dedicated U-500 insulin syringe. These dedicated devices, if approved, will allow administration of HumuLIN R U-500 in actual units without dose conversion to non-dedicated syringe markings (unit markings with a U-100 insulin syringe or volume [mL] markings with a volumetric syringe). Due to the complexity and risks inherent in device development and regulatory review, the company is unable to speculate on the timing of availability of these devices. Until then, HumuLIN R U-500 must be administered using a U-100 insulin syringe or a volumetric (tuberculin or allergy) syringe. Stay tuned for more information.