This Week’s Question:
According to the JNC 7 guidelines, use of fixed low-dose combination
therapy with any of several different approved combinations of antihypertensive
agents can be recommended. However, for which of the following reasons
is fixed-dose therapy not generally applicable?
1. To improve patient
adherence to therapy
2. As a "standard of care" for all patients with blood pressure
levels > 140/90 mm Hg
3. To minimize side effects by using lowest effective doses of each
agent
4. To provide a rapid response in those patients requiring a 20/10-mm
Hg decrement in blood pressure levels
