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Diabetes In Control.com  Issue #141  February 6, 2003 

Test Your Knowledge 

Mrs. F. is a 60 year old woman with a 10 year history of type 2 diabetes, she has documented nephropathy with a creatinine of 1.3 mg/dl. Her glycemic control has however deteriorated over the 6-12 months despite maximal dosage of an glucosidase inhibitor such as acarbose and sulfonylurea.

Her HbA1c has risen from 8.5% to 9.6% in the last six months. You elect to discontinue the acabose / sulphonylurea combination, your next intervention would be: 

  1. Refer her to an endocrinologist for consideration of an insulin pump.
  2. Add metformin to her regimen.
  3. Institute treatment with bedtime insulin and a sulfonylurea.
  4. Institute treatment with intensive insulin therapy.


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