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Type 2 Diabetes


Table of Contents

Articles

AACE: Why Physicians Delay the Start of Insulin in Type 2 Diabetes Patients

The perception that insulin therapy may be too burdensome for patients has led primary care physicians to delay the use of insulin therapy in patient with type 2 diabetes....


How Type 2 Diabetes Develops

New mouse model shows how type 2 diabetes might develop....


Hormone from Fat May Play Key Role in the Treatment of Type 2 Diabetes

Elevated levels of a hormone released from adipose tissue may be the key link in the development of type 2 diabetes in obese patients....


AACE - New Diabetes Guidelines Based on Tailored Approach

AACE calls for a new guideline based on a tailored approach to treating type 2 diabetes while maintaining the use of an algorithm-based model....


Low Melatonin Doubles Diabetes Risk

The evidence for a link between the body clock hormone melatonin and type 2 diabetes continues to mount....


New Markers Predict When Diabetic Patients Develop Cognitive Decline

Stroke and subclinical markers of vascular disease may help predict which older patients with type 2 diabetes will develop cognitive decline....


Being Overweight and Drinking Increases Risk for Liver Damage

Women are at even higher risk for chronic liver disease....


No Link between Diabetes Remission, Weight Regain after Gastric Bypass

Weight regain among diabetic patients who have undergone gastric bypass is not associated with remission of diabetes....


AACE Releases New Comprehensive Diabetes Management Algorithm

For treatment of diabetes and prediabetes patients.... 


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #30: Macrovascular Complications, Part 2

Richard S. Beaser, MD Michael Johnstone, MD


Diabetic Emergencies, Diagnosis and Clinical Management: Sick-Day Rules in Diabetes, Case Studies

Konstantinos Makrilakis, Nikolaos Katsilambros  


Joslin's Diabetes Deskbook, Updated 2nd Ed., Excerpt #27: Physical Activity for Fitness, Part 4

Richard S. Beaser, MD, Edward S. Horton, MD and Catherine A. Mullooly, MS, RCEP,...


More Than 50 Ways to Prevent Diabetes

This tip sheet helps patients at risk for...


Editor's Note DCMS #67: Adolescents and the Process of Change

It has been said that, "People cannot influence their motivation and actions very well if they do not pay adequate attention to their own performances, the conditions under which they occur, and the immediate and distal effects they produce."...


Is Engaging in Intense Exercise for Less Time the Answer?

By Sheri Colberg,...


United States of Diabetes Report

  You can use the information in this report to provide evidence for your ...


Editor's Note: New Homerun Slides on CVD

Over the past weeks we have shared some great slides on Advanced Glycation End-products, and there's a lot linking these...


Role of DPP-4 Inhibitors in Clinical Practice

The dipeptidyl peptidase-4 (DPP-4) inhibitors are a newer class of oral drugs for the treatment of type 2 diabetes. They inhibit the breakdown of glucagon-like peptide-1 (GLP-1) and increase the incretin effect in patients with type 2...


Dr. Aaron I. Vinik on Early Insulin Use in the Progression of Diabetes

One of the leading diabetes researchers in the world, Dr. Aaron I. Vinik, Director of Research and...


Early Use of Insulin to Improve Beta Cell Preservation

By David Joffe, BSPharm, CDE; Steve Freed, BSPharm CPT; Brandon Flohr and Vanessa Cepero, PharmD candidates, LECOM College of Pharmacy Type 2 diabetes is a heterogeneous disorder, characterized by...


Managing Clinical Problems in Diabetes, Case Study #18: Complementary and Alternative Therapies

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Managing Clinical Problems in Diabetes, Case Study #17: Health Assessment, Management Targets, and Deciding on a Management Plan

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Managing Clinical Problems in Diabetes, Case Study #14: Diagnosis and Classification

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Letter from the Editor #582

The National Committee for Quality Assurance (NCQA) recently held a series of webinars to help clinicians in "Achieving and Outperforming Type...


GLP-1 Special Series Editor's Note #6

This week we get back to our interview with Dr. Aaron Vinik, Director, EVMS Strelitz Diabetes Research Center. He has been at the forefront in developing new technologies for growing and regenerating beta cells. Our publisher, Steve...


Dr. Vinik Answers Our Best Questions on GLP-1 Therapy

This week, after our publisher Steve Freed was able to connect up with Dr. Vinik again,...


Managing Clinical Problems in Diabetes, Case Study #12: Psychological Issues and Quality of Life

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath Mrs. MJ was referred to a diabetes centre by her GP....


Letter from the Editor: We Bring You the Best of the ADA

Steve and Andrew came home with tons of new information from the recent ADA 71st Scientific Sessions. We are going to be sharing the information with you for the next couple of weeks as we continue to review and evaluate the...


Managing Clinical Problems in Diabetes, Case Study #11: Taking Care of the Caregiver

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Editor's Note: Knowing Your A1c and Learning How to Use an Insulin Pen Correctly

While I was talking to a large group of employees on the west coast of Florida, I made the comment that if you are over 40 and have a family history of diabetes, overweight, hypertension or have elevated lipids, you should get an A1c test at...


Managing Clinical Problems in Diabetes, Case Study #7: Mrs. RS

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Managing Clinical Problems in Diabetes, Case Study #6: Mrs. KB

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


"Where Do I Begin?" Booklet

  This booklet, available in English and ...


Diabetes Info from the CDC on Diabetes and Pre-diabetes

Data sources, methods and references for estimates of diabetes and pre-diabetes to use for...


Diabetes and Healthy Eyes Toolkit

New Toolkit for Community Health Workers to Educate People...


Unexplained Weight Loss and Decreased Insulin Needs in Severely Obese Type 2 Patients

by Ashley Berry, Mercer University Doctor of Pharmacy Candidate 2011    Is it possible for an obese Type 2 diabetic patient who administers large quantities of insulin daily to b...


Letter from the Editor: More CDC Data, LTC Caregiver and Patient Education, and the Latest Diabetes Management Apps

The CDC just released new data in their 2011 fact sheet which got overlooked in most journals. They now estimate that 26.9% of all patients over 65 have diabetes. This is almost 11 million patients and many of them...


ADA/PDR: Medications for the Treatment of Diabetes, Ch. 18, Pt. 1

Diabetic Neuropathic Disorders


Diabetes Disaster Averted #22: Unexpected Side Effects

A 58-year-old male with a history of Type 2 diabetes and nonalcoholic steatohepatitis (diagnosed in 2006) presented to a clinic for diabetes management. At the time, the patient's aspartate aminotransferase (AST) was 53 U/L...


Tool for Your Practice: Diabetes Alert Day Tools

Diabetes Alert Day Kit Do your part for ALERT!...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt 5

Long-Term Complications and Treatments


Letter from the Editor: Diabetes in a Cup

This week I stopped at a Grab and Go Gas Mart on the way home from a program in Sarasota to get a drink. When I was at the fountain I found that the 44 ounce was no longer the largest size as a new 52 ouncer was on the...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt 4

Long-Term Complications and Treatments


Letter from the Editor #559: Listening to "News" on the Radio...

Typically whenever I hear something on TV or the radio about diabetes my ears perk up and I listen carefully. This past week there were a few things that caught my attention. First I heard...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt3

Long-Term Complications and Treatments


Letter from the Editor: CDC Numbers Show Dramatic Increase in Diabetes

The official numbers from the CDC are out for 2011 and once again the number of patients with diabetes is up. Last year my PowerPoint slides topped out at 24 million but this year the CDC has upped the number to nearly 26 million Americans. At this...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt2

Long-Term Complications and Treatments: Dyslipidemia


Diabetes Disaster Averted #18: Even the Most Experienced Make Mistakes

A 53-year-old Hispanic woman presents for an initial evaluation of Type 2 diabetes. The patient was first diagnosed with Type 2 diabetes 15 years ago. She has since been noticing mild paresthesias of the feet....


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt1

Long-Term Complications: Macrovascular


Tool for Your Practice: AADE Super Bowl Game Day Tips for People with Diabetes

Despite what many think, diabetes does not have to deter people who have the disease from enjoying Super Bowl Sunday parties along with everyone else, according to the American Association of Diabetes Educators (AADE). In fact, managing your...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 14, Pt2

Metabolic: Hyperosmolar Hyperglycemic Nonketotic Syndrome


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 14, Pt1

Acute Complications: Metabolic - DKA


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 13-Pt 4

Assessment of the Treatment Regimen, Part 4


Letter from the Editor:

This week we have an article about the use of glycated albumin for monitoring fluctuating and poorly controlled Type 2 diabetic patients. The authors...


Editor's Note: Diabetes and Cardiovascular Disease, Lifestyle Habit Changes, and More....

Every week there is a new study coming out showing the relationship between diabetes and cardiovascular disease. There are over 1.1 million Americans who will have a serious heart attack in 2011 and there are over 80 million who have one or more...


Diabetes Disaster Averted #13: Managing Weight-Loss Insulin Changes

I recently started working with a 58 y/o gentleman who had insulin dependent Type 2 diabetes. He was 110 pounds overweight, and was using 120 units of Lantus and 30 units of Humalog daily. His most recent A1c was 8.6....


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 13-Pt 3

Assessment of the Treatment Regimen, Part 3


Editor's Note: Inflammation Markers, Treatment Regimens and Patient Confusion

Last week our publisher, Steve Freed, shared some great Homerun Slides on how Type 2 diabetes develops and what role hormones play in the progression of the disease. Your response was overwhelming and this week Steve brings us the second...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 13-Pt 1

Assessment of the Treatment Regimen


Exercise and Type 2 Diabetes

The American College of Sports Medicine and the American Diabetes Association: joint position statement  


Tool for Your Practice: Challenges and Opportunities to Control Diabetes

Challenges and Opportunities to Control Diabetes This new report,...


Editor's Note: The Bergenstal/Kendall Slide, Treatment Algorithms and More

Lecture after lecture we all have seen the famous slide first done by David M. Kendall, MD, Richard Bergenstal, MD, et al, at the International Diabetes Center in Minneapolis. I have used that slide in over 100 presentations and I would guess it...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 12-Pt 1

Treatment Algorithm


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 11-Pt 3

Pramlintide Therapy


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 11-Pt 2

Pramlintide Therapy


Santarus Announces Launch of Type 2 Diabetes Drug CYCLOSET®

CYCLOSET is the first in-class and only centrally acting dopamine agonist oral antidiabetic....


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 11-Pt 1

Pramlintide Therapy, Chapter 11 - Part 1


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 9-Pt 6

Insulin-Pump Therapy + New Types of Insulin Preparations + Complications of Insulin Therapy, Chapter 9 - Part


Diabetes Rising: What Can We Do to Stop It Before It's Too Late?

By Sheri Colberg,...


Editor's Note: Multiple Insulin Regimens and HOMA

As patients progress through the stages of diabetes from the simple use of Metformin to complex basal/bolus insulin regimens there are many stops along the way. This week Dr. Edelman and Dr. Henry focus on multiple shot insulin regimens for Type 2...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 9-Pt 5

Multiple-Injection Regimens, Chapter 9 - Part 5


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 9-Pt 4

Combination Therapy, Chapter 9 - Part 4


Diagnosis and Management of Type 2 Diabetes, Tenth Edition, Ch 9, Pt 3

Application of Intensive Insulin Therapy, Chapter 9 - Part 3


Diagnosis and Management of Type 2 Diabetes, Tenth Edition, Ch 9, Pt 2

Selecting an Insulin Preparation, Chapter 9 - Part 2


Editor's Note: Presenting the Diabetes Clinical Mastery Series

This week we are pleased to present our new Diabetes Clinical Mastery Series...


Diagnosis and Management of Type 2 Diabetes, Tenth Edition

Insulin Therapy, Chapter 9 - Part 1 Steve V. Edelman, MD, Professor of Medicine, Division of Endocrinology and Metabolism, University of California, San...


Managing Type 2 Diabetes: Balancing HbA1c and Body Weight

Annie A. Mavian, DO; Stephan Miller, PhD; and Robert R. Henry, MD Abstract: Most patients with type 2 diabetes present with comorbid overweight or obesity. Reaching and maintaining acceptable glycemic control is more difficult in...


A Review of Insulin Pen Devices

Emily K. McCoy, PharmD and Bradley M. Wright, PharmD, BCPS Abstract: Optimization of glycemic control is a fundamental aspect of diabetes management, and rates of diabetes-related microvascular complications are significantly...


How to Obtain Appropriate Type 2 Diabetes Control in the First 180 Days of Treatment Initiation

Louis Kuritzky, MD; Benjamin J. Epstein, PharmD, BCPS; and Frank Lavernia, MD Abstract: Good control of diabetes provides meaningful microvascular risk reduction; yet, patients with type 2 diabetes mellitus commonly languish at...


Effective Switch From Premixed to Basal-Prandial Insulin to Achieve Glycemic Goals in Type 2 Diabetes

Frank Lavernia, MD Abstract: Objective This article describes a patient with type 2 diabetes mellitus achieving glycemic control after transitioning from premixed to basal-prandial insulin.


Partnering with Patients to Improve Therapeutic Outcomes: Incretin-Based Therapy for Type 2 Diabetes

Daniel A. Nadeau, MD Abstract: The prevalence of type 2 diabetes mellitus has reached epidemic proportions. Current treatment options for patients with diabetes include lifestyle modifications (eg, diet and exercise) along with...


Hyperglycemic Emergencies

Lana Kravarusic Doctor of Pharmacy Candidate, University of Florida 


Review: Prescription for Type 2 Diabetes: EXERCISE by Milt Bedingfield, MA, CDE

Katy Wallis,...


Letter from the Editor: Quinine, Avandia and a Prescription for Type 2 Diabetes: EXERCISE!

It is not often that I venture out of the diabetes arena. However, this week I wanted to start out by reminding you that the FDA is again issuing a strong warning not to prescribe quinine for your patients who complain of leg cramps. This...


Essential Oils for the Management of Type 2 Diabetes

Ivory A. Gordon, Pharm.D....


Testosterone Gel Improves Diabetes in Men with Low Levels

News from the British Endocrine Society meeting  MANCHESTER, England -- Topical testosterone replacement reduced insulin resistance and glycated hemoglobin in men who were deficient in the hormone and at ...


How to Easily Reap the Health Benefits of Physical Activity

By


Get Your Kids Moving, Too

 


Oprah's Outpouring: A Bittersweet Commentary on Responses to Her Diabetes Show

Theresa Garnero, APRN, BC-ADM, MSN,...


America's Silent Killer: Oprah and Dr. Oz Want to Save Your Life

By...


The 30 Day Challenge

Combination Therapy: Oral medications during the day and Lantus at night


Being Female and Athletic: Special Concerns for Diabetic Women Only

If your patients are female, past puberty, and still young enough to be menstruating, then you’ll want to read what Sheri Colberg, Ph.D., FACSM, has to say in this week’s feature; Being Female and Athletic: Special Concerns for Diabetic...


New Perspectives In Oral Care For Those With Type 1 And Type 2 Diabetes

Charles W. Martin, DDS, founded DentistryForDiabetics, a nationwide group of dentists committed to helping those with diabetes. He authored the book Don’t Sugarcoat it: The Story of Diabetes and Dentistry and we are happy that he has joined...


New Test For Diagnosis of Diabetes and Pre-Diabetes

The ADA and other organizations will be announcing the guidelines on how to use the A1c test to diagnose diabetes. The test that has been used by most doctors is the fasting blood glucose test. The problem with the fasting blood glucose is that...


Recent Advances in GLP-1 Receptor Agonists in the Treatment of Type 2 Diabetes

A couple of months ago we had a review of GLP-1 mimetic therapies and studies form the European Association for the Study of Diabetes (EASD) 44th Annual Meeting convened in Rome, Italy, September 8-11, 2008. Many of you emailed me asking for more...


Your First Year with Diabetes: What to Do, Month by Month

For the past 5 years Theresa Garnero, APRN, BC-ADM, MSN, CDE, has brought us some great laughs with her diabetes cartoons. But all those letters after her last name also means she knows something about diabetes care. She has just completed the book...


HIV-infected patients are at an increased risk for developing Diabetes

More and more patients with HIV are controlling their disease well. When viral loads are under control, patients often are seen by clinicians for other problems. Diabetes seems to be one of those problems that get a lot of attention. My current...


Preteens, teens doubled use of diabetes drugs

A recent article in Pediatrics, discussed how preteens and teens have doubled use of diabetes drugs in the past 4 years and that the prevalence is dramatically higher among young girls vs. boys. Why is this occurring? Why is it higher in girls?...


“Because The Light’s Better Here!”

Why Focusing On Intensive Glucose Control With Drugs Alone Is Counterproductive


DIABETES & DEPRESSION: Letter from a Reader: Focusing on “The Can’ts”

In my last article, “Recognizing & Approaching Depression”, I promised to provide suggestions you could make to patients struggling with depression. I will do that in my next article. For now however, I’d like to answer an email sent to Diabetes in...


How the Liver Affects Insulin and Vice Versa: Part 2, Obesity and Lipid Metabolism

Andre McMahon, PharmD Candidate, University of Florida College of Pharmacy Dave Joffe, Editor-in-chief, Diabetes In...


Presentations

Core Defects of Type 2 Diabetes, Part 2 of 4

  This week's set of Homerun Slides topics include: The Role of Incretins in Type 2...


SGLT-2 Inhibitors: A New Modality for Treating Type 2 Diabetes

In this first set of Homerun Slides for our new Special Edition series on SGLT-2 Inhibitors, we give you a brief...


Diabetes Update, Part 2 of 3

  In this week's Homerun Slides series, we go over why there is so much interest in the...


Diabetes Mellitus 101 for Medical Professionals, Part 6 of 9

In this week's Homerun Slides, we present Part 6 of Dr. Stanley Schwartz's series on...


Diabetes Mellitus 101 for Medical Professionals, Part 4 of 9

In this week's Homerun Slides, we continue with Part 4 of our series from Dr. Stanley...


Diabetes Mellitus 101 for Medical Professionals, Part 3 of 9

In this week's set of Homerun Slides, we discuss whether it is possible to delay the...


Diabetes Mellitus 101 for Medical Professionals, Part 2 of 9

In this week's set of Homerun Slides,...


Diabetes Mellitus 101 for Medical Professionals, Part 1 of 9

This week we begin a new Homerun Slides series on Diabetes Mellitus 101 for ...


The Role of DPP-IV Inhibitors in the Management of Type 2 Diabetes


Incretins, Part 4 of 7

In this week's Homerun Slides, we cover DPP-IV inhibitors including a comparison of...


Incretins, Part 1 of 7

This first of seven sets of Homerun Slides begins with GLP-1 physiology, then examines ...


Pathophysiology in the Treatment of Type 2 Diabetes: Newer Agents, Part 5

This week we conclude our five-part series of Homerun Slides on Pathophysiology in the...


Pathophysiology in the Treatment of Type 2 Diabetes: Newer Agents, Part 3

We continue this week with our


Pathophysiology in the Treatment of Type 2 Diabetes: Newer Agents, Part 2

  This week we continue our series of Homerun Slides on Pathophysiology in the ...


Pathophysiology in the Treatment of Type 2 Diabetes: Newer Agents, Part 1

This week we begin a new five-part Homerun Slides series on Pathophysiology in the...


Insulin Resistance, Part 2: Inflammation Markers

Plasminogen is an acute phase protein and precursor to plasmin, which...


Insulin Resistance, Part 1

The prevalence of Type 2 diabetes mellitus (DM) has increased dramatically over...


Glycemic Disorders Part 1

The slides in this section provide an overview of the...


Screening for Diabetes and Pre-Diabetes

Patients who...


 
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