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Type 1 Diabetes


Table of Contents

Articles

Infection Linked to Injecting through Clothing

After extending incubation period for cultures, non-tuberculous mycobacteria cutaneous infection was found on woman injecting insulin through clothing....


Type 1 Diabetes Triggered by Animal Infection?

Study shows peaks and clusters of type 1 diabetes, paralleling viral patterns....


Increases in an Inflammatory Protein Leads to Heart Disease

An inflammatory protein, calprotectin, links hyperglycemia to myelopoiesis and the increase risk of coronary heart disease....


AACE: Degludec Shows Efficacy in Type 1 Diabetes

Type 1 diabetes patients had lower rates of nocturnal hypoglycemia with once-daily doses of insulin degludec versus similar doses of insulin glargine....


ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #1: Diagnosing Diabetes

Anne Peters, MD, and Lori Laffel, MD, MPH, editors Jane Lee Chiang, MD, managing editor


Discovery Raises Hope for Type 1 Diabetes Reversal

A two-step process consisting of one drug to induce immune tolerance and another to promote islet regeneration could be key to type 1 diabetes reversal....


Leptin Gene Therapy Possible New Option in Treating Diabetes and Obesity

Leptin therapy studies are looking very promising for the treatment of diabetes in both type 1 and 2 patients.... 


Vitamin D Deficiency in Type 1 Diabetes Patients

Vitamin D supplementation for the prevention of the onset of type 1 diabetes is also being studied.... 


Positive Results for Next Once A Week GLP-1

Five studies show positive results for new GLP-1 drug dulaglutide....


New Pill in the Works for Type 1 Patients

Protein that lowers blood sugar may be new oral diabetic agent for type 1 patients....


Diabetes Vaccine

"Bacillus-Calmette-Guerin vaccine may cause TNF release to destroy autoimmune cells attacking the pancreas."... 


Insulin Requirements Increased by High-Fat Meals

An increase in dietary fat can raise glucose levels and insulin requirements in patients with type 1 diabetes....


Protein Doesn't Affect Post-prandial Glucose Levels in Type 1's

Study shows type 1 diabetes patients do not need to adjust their flexible insulin scale based on the amount of protein they are about to consume....


More Active Type 1 Diabetes Patients Use More Carbohydrates and Have Higher A1c Values

More active type 1 diabetes patients are at a greater risk for hypoglycemia and therefore may consume an increased amount of carbohydrates....


Reduced Pain, Increased Compliance, Faster Kinetics with Intradermal Injection in Type 1 Kids

Intradermal insulin injection via a microneedle provided less pain and increased kinetics....


Novo Nordisk Creates Insulin Pill

Insulin tablets' safety, tolerability, exposure, and effect on blood glucose levels were tested in a clinical trial....


Artificial Pancreas Beats Insulin Pump

Artificial pancreas reduces nighttime hypoglycemia and improves control compared to an insulin pump....


Type 1 Diabetes Increases Risk for Thyroid Disease

Type 1 diabetic patients are at higher risk of developing autoimmune thyroid condition and women are eight times more likely to develop thyroid disease than men....


Diabulimia: the Diabetic Eating Disorder

Diabetic patients are more than twice as likely to have an eating disorder….


Joslin's Diabetes Deskbook, Updated 2nd Ed., Excerpt #27: Physical Activity for Fitness, Part 4

Richard S. Beaser, MD, Edward S. Horton, MD and Catherine A. Mullooly, MS, RCEP,...


Possible Type 1 Cure Normalizes Blood Sugars

After a single gene therapy session, the dogs recover their health and no longer show symptoms of the disease for over 4 years....


Type 1 Diabetes Up 70 Percent in Kids in U.S.

Experts suspect the jump may be linked to unknown environmental causes....


Closed-loop Delivery System Reduces Hypos and Improves Control

A pump with two chambers, one for insulin and one for glucagon can….


Type 1 Children Not Meeting Targets

Less than a third of youth with type 1 diabetes are meeting recommended A1c targets....


Which Is More Important: Blood Sugar, Blood Pressure or Cholesterol Targets?

For people with diabetes, meeting the recommended guidelines for blood pressure and cholesterol is….


Alzheimer's Linked to Diabetes

Both type 1 and type 2 diabetes have been linked to cognitive problems like Alzheimer's disease and dementia....


Pancreas Size a Marker for Diabetes

The smaller pancreas that is often found in patients with type 1 diabetes was also seen in people at risk for the disease, pointing to a possible diabetes biomarker....


Treat Type 1 to Treat Atherosclerosis

Pancreatic islet transplantation in type 1 diabetes may improve atherosclerosis....


Type 1 to Triple, Type 2 to Quadruple in Youth

The numbers of young people with both type 1 and type 2 diabetes are likely to rise dramatically during the next 40 years, particularly among minority populations....


How the Liver Affects Insulin and Vice Versa: Part 1 Carbohydrate Metabolism

Dave Joffe, Editor-in-chief, Diabetes In Control Andre McMahon, Ben Mitrano, PharmD Candidates, University of Florida College of...


Four-Fold Increase for Chronic Liver Disease for Type 1's

Patients with type 1 diabetes displayed a greater risk for developing chronic liver disease, including a fourfold prevalence for cirrhosis, compared with the general population....


Dose-Response Relationship between Vitamin D and Type 1 Diabetes

A correlation has been found between vitamin D3 serum levels and subsequent incidence of type 1 diabetes....


Stem Cell Breakthrough May Bring Us Closer to a Cure

In a breakthrough that signifies a move toward a cure for type 1 diabetes, Australian researchers have identified stem cells in the pancreas that can be turned into insulin-producing cells....


Diabetes Deaths Fall 61%

According to the CDC, the death rate from diabetes among children and adolescents has fallen by more than 60% since the late 1960s....


New Simpler C-Peptide Test Available

A single blood test measuring C-peptide at 90 minutes after a mixed-meal challenge was a sensitive and specific measure of endogenous insulin secretion among children with new-onset type 1 diabetes.... 


EASD: Kidneys Tell of Heart Risk in Type 1 Diabetes

Researchers report that, for type 1 diabetes patients who have good glycemic control, renal function may predict their risk of developing heart disease....


Teens Manage Diabetes Better with Family Problem-solving Sessions

A clinic-based program for adolescents with type 1 diabetes and their families helped the teens develop the healthy behaviors needed to control their blood sugar levels....


Absence of Certain Proteins Causes Diabetes, and Rheumatoid Arthritis

The absence of related protein molecules, Puma and Bin, prompts immune cells to turn against human organs they are meant to protect and cause type 1 diabetes and rheumatoid arthritis....


More Good News on Degludec

Better control can be achieved with fewer injections than the traditional basal bolus therapy used in type 1 diabetes....


Moms with Diabetes and Low Income May Lead to Child's ADHD

Gestational diabetes may raise ADHD risk in type 1....


HbA1c Greater than 6.5% Is Specific, Not Sensitive for T1DM Youth

Across four studies, HbA1c ≥ 6.5 percent a specific, but not sensitive, early indicator of T1D in youth....


Walking after Eating Lowers Glucose in Healthy People and Diabetes Patients

Walking or other light exercise after meals may reduce glucose levels by more than half in both healthy people and type 1 diabetes patients....


Gastric Emptying Remains Stable over Time for Type 1 and Type 2 Diabetes

Gastric emptying of solids and liquids, and gastrointestinal symptoms remain stable over time in patients with long-term type 1 and type 2 diabetes....


Faustman's Type 1 Diabetes Cure Raises Debate

Dr. Denise Faustman's announcement of the results of a small study of a handful of type 1 patients showing the regeneration of beta cells with the use of a TB vaccine that has been available for years is causing a controversy in the medical...


New System Controls Overnight Glucose Levels in Type 1 Diabetes

Researchers have developed a new automated, portable glucose control system which safely manages overnight glucose levels in adolescents and young adults with type 1 diabetes.... 


Lifespans for Type 1 Diabetes Patients Getting Longer by 15 Years

Life expectancy significantly increased among individuals with type 1 diabetes during a 30-year, long-term prospective study....


Pramlintide + Insulin in Closed Loop System Improves Glucose Control

Adding pramlintide before meals improves blood glucose control in patients with type 1 diabetes receiving insulin through an external closed-loop artificial pancreas system....


Cholecalciferol Preserves Beta-Cell Function in Type 1 Patients

In a small randomized trial, cholecalciferol helped preserve beta-cell function in patients with new-onset type 1 diabetes....


Newer Technologies Work Better than Conventional Methods in Controlling Glucose

Newer technologies designed to help people with type 1 diabetes monitor their blood sugar levels daily work better than traditional methods.... 


ADA: First U.S. Type 1 Registry with 25,000 Participants Publishes Results

In the most comprehensive analysis of people with type 1 diabetes ever undertaken in the U.S., researchers found that....


ADA: Diabetes Patients Shed Pounds with Insulin Analog

An investigational basal insulin analog, LY2605541, may actually help type 1 and type 2 diabetic patients lose weight....


ADA: First Type 1 Registry in the U.S.

Newly created registry includes 25,000 people of all ages. What they found was that most type 1's are…. 


ADA: Both Type 1 and Type 2 Diabetes Rates Increase Significantly among American Youth

The prevalence of both type 1 and type 2 increased among young people substantially over the past decade. Researchers also found that complications such as nerve damage are…


Heart Rate Affected by Nocturnal Hypoglycemia in Type 1's

Hypoglycemia linked to reduction in low-frequency component of heart rate variability in type 1 diabetes....


AACE: Prediction and Prevention of Type 1 Diabetes

Drugs aimed at halting the molecular destruction of beta cells are likely the next step in the quest to stop the progression of autoimmune type 1 diabetes....


Changes in the Eye Can Predict Heart Disease for Diabetes Patients

Arterial narrowing in retina seen as independent risk factor with type 1 diabetes.... 


Immune Cell Therapy Possible Diabetes Cure

An experimental therapy that reprograms the immune system then spurs the growth of healthy insulin-producing cells reversed late-stage diabetes in mice.... 


Ultra-Long-Acting Insulin Degludec, Two New Studies

Two published Phase III studies reveal that ultra-long-acting insulin degludec considerably reduced rates of....


Artificial Pancreas Testing Approved for Outpatients

  The FDA has approved a key testing phase for an artificial pancreas developed by researchers of the University of Virginia, which could potentially automate care for millions of those with type 1 diabetes....


Diet Soda May Increase Glucagon-Like Peptide 1 Levels

The increase was seen in healthy youths and those with type 1 diabetes, but not in those with type 2 diabetes....


Why WBCs Attack Beta Cells in Type 1 Diabetes

Many genes that influence type 1 diabetes are also found in pancreatic beta cells suggesting that the insulin-producing cells play a role in why white blood cells attack the beta cells leading to type 1 diabetes, according to new research from...


Insulin Production Persists Decades after Diagnosis of Type 1 Diabetes

C-peptide production and beta cell functioning is detected decades after disease onset, which may contribute to the growing body of evidence suggesting there might be a longer window for therapeutic intervention....


Lifting Weights before Cardio Benefits People with Diabetes

People with diabetes may have better blood sugar control during workouts if they lift weights before doing cardio exercise....


Duration of Diabetes Raises Stroke Risk

The risk of ischemic stroke increased by 3% for each additional year a patient had diabetes....


Type 1 Diabetes Linked to Lower Fertility

Significantly fewer children are born to couples when one partner has type 1 diabetes....


Bolus Calculation, Flexible Insulin Ups Diabetes Control

A structured course teaching the benefits of automated bolus calculator use and flexible intensive insulin therapy improves metabolic control and satisfaction in patients with type 1 diabetes....


Type 1 Develops More Slowly Than Thought

Study finds gradual decline in insulin production, which could extend treatment options....


Excess Mortality for Adults with Young-Onset Diabetes Persists

Excess mortality rates persist among adults with young-onset diabetes, and are mainly due to ESRD and CAD....


Autoantigen Treatment Benefits Type 1's

Autoantigen treatment of new-onset type 1 diabetes was unsuccessful in preserving pancreatic beta-cell function overall, but the treatment did appear to help in certain prespecified patient subgroups....


How Type 1 Diabetes Makes You Stronger

  New website for your patients with type 1 diabetes featuring engaging and inspiring videos...


Women with Diabetes Are Four Times More Likely to Have a Baby with Birth Defects

Pregnant women with diabetes are almost four times more likely to have a baby with a birth defect than women without the condition, and the likelihood is linked to the mother's glucose level....


New Information on Link between 'Killer Cells' and Diabetes

Our own killer T-cells in the human body which help protect us from disease may inadvertently destroy cells that produce insulin....


Stem Cell Therapy May Reverse Diabetes

An immune regulator from healthy cord blood stem cells (CB-SCs) can "educate" the T cells of a person with type 1 diabetes, enabling the pancreas to produce insulin....


Predicting Kidney Disease in Diabetes Using Tumor Necrosis Factors

According to the results of two 12-year studies, levels of circulating tumor necrosis factor receptor 1 and 2 (TNFR1 and TNFR2) predicts kidney disease in both type 1 and type 2 diabetes....


Stem Cell Therapy May Reverse Diabetes

An immune regulator from healthy cord blood stem cells (CB-SCs) can "educate" the T cells of a person with type 1 diabetes (T1D), enabling the pancreas to produce insulin....


Insulin Therapy May Help Reduce Cardiovascular Disease

Diabetes patients are more susceptible to the development of atherosclerosis than non-diabetics and insulin therapy might help repair atherosclerotic lesions in diabetic patients....


Psychology in Diabetes Care, 2nd Ed., Part 11

Edited by Frank J. Snoek and T. Chas Skinner Diabetes in Adolescents


Should Metformin Be Used for Type 1 Diabetes?

The addition of off-label metformin to insulin therapy to improve insulin sensitivity, promote weight control, and reduce insulin dose requirements in patients with type 1 diabetes, has been assessed in systematic reviews....


Medtronic Remote Diabetes Monitor Gets U.S. Approval

Medtronic Inc. has announced it has received regulatory approval for the first remote glucose monitor that will let parents check the blood sugar of a diabetic child sleeping in another room....


New Protein May Be a Treatment Target for Type 1 Diabetes

Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have discovered a new protein that may play a critical role in how the human body regulates blood sugar levels and could be a new target...


JDRF Adopts New Brand and Logo to Better Reflect its Mission for Type 1 Diabetes

The new logo, tag line, and simpler name are part of an effort to clarify the organization's work for all people with type 1 diabetes and to increase understanding about the disease....


Memory is Altered in Patients with Type 1 Diabetes During Hypoglycemia

Brain activation was increased and deactivation was decreased in type 1 diabetic versus control subjects during hypoglycemia....


United States of Diabetes Report

  You can use the information in this report to provide evidence for your ...


Scientists Discover a New Treatment for Type 1 Diabetes

Scientists discover that the beta-cells need heparin sulphate to survive....


Psychology in Diabetes Care, 2nd. Ed, Part 9

Edited by Frank J. Snoek and T. Chas Skinner Diabetes in Adolescents


Intensive Type 1 Diabetes Therapy Lowers Kidney Failure Risk by 50 Percent

Intensive therapy for type 1 diabetes mellitus lowers the long-term risk for impaired glomerular filtration rate (GFR)....


Closed-Loop Insulin Pump Effective and Safe in Pregnancy

Insulin delivery with a closed-loop system was at least as effective as continuous subcutaneous insulin infusion in a UK study of pregnant women with type 1 diabetes....


Team Type 1-SANOFI Running Team Begins 3,000 Mile Cross Country Run

Oceanside, CA – On Thursday, October 25, ten members of the Team Type 1-SANOFI running team embarked on the journey of a lifetime. The athletes, who all have Type 1 diabetes,...


Diabetes Disaster Averted #46: When It's Too Hot to Handle

I recently had one of my long term type 1 patients on an insulin pump run into a big problem. She had been on an older pump for about 5 years and had recently changed brands because of the features of the newer pump….


ADA: Advances in Treating Type 1 Diabetes: An Overview of the Latest Developments

Drugs Show Promise for Preserving Body's Ability to Produce Insulin The progression of type 1 diabetes may be slowed in those newly diagnosed through the use of promising new...


Letter from the Editor #581: Exenatide News and Type 1 News from the ADA

There was a news release that caught my attention this past week. Eli Lilly announced that the Exenatide tQT Study Showed...


Diabetes Disaster Averted #41: Glucagon Mini-Dosing -- A Valuable Tool

My son Jason was diagnosed with Type 1 diabetes at the age of 3. As a medical professional I felt fairly confident in the use of a Glucagon Kit in an emergency. But I never needed to use it until one morning over a weekend....


Editor's Note: Knowing Your A1c and Learning How to Use an Insulin Pen Correctly

While I was talking to a large group of employees on the west coast of Florida, I made the comment that if you are over 40 and have a family history of diabetes, overweight, hypertension or have elevated lipids, you should get an A1c test at...


Managing Clinical Problems in Diabetes, Case Study #10: Osteomyelitis

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Diabetes Disaster Averted #36: Mixing Insulins

Recently I saw a type 1 DM patient diagnosed in 1980 at 15 years of age. She had not seen an educator in quite some time but had changed from NPH/Regular to Lantus & Regular....


History of Type 1 Diabetes Treatments

by Huong-Thao Le, 2011 Doctor of Pharmacy Candidate LEECOM, Bradenton, FL The discovery of insulin in 1921 was one of the greatest medical breakthroughs in history. Individuals, mostly children with...


Letter from the Editor: History of Insulin Therapy and New Diabetes Treatment Possibilities

Last week I was discussing insulin therapy with my interns as we were evaluating insulin choices for a local physician. The consensus was to start on a long acting insulin like glargine and then titrate based on glucose levels with a patient...


Diabetes Info from the CDC on Diabetes and Pre-diabetes

Data sources, methods and references for estimates of diabetes and pre-diabetes to use for...


Diabetes and Healthy Eyes Toolkit

New Toolkit for Community Health Workers to Educate People...


Letter from the Editor: More CDC Data, LTC Caregiver and Patient Education, and the Latest Diabetes Management Apps

The CDC just released new data in their 2011 fact sheet which got overlooked in most journals. They now estimate that 26.9% of all patients over 65 have diabetes. This is almost 11 million patients and many of them...


ADA/PDR: Medications for the Treatment of Diabetes, Ch. 18, Pt. 1

Diabetic Neuropathic Disorders


Letter from the Editor: Diabetes in a Cup

This week I stopped at a Grab and Go Gas Mart on the way home from a program in Sarasota to get a drink. When I was at the fountain I found that the 44 ounce was no longer the largest size as a new 52 ouncer was on the...


Letter from the Editor #559: Listening to "News" on the Radio...

Typically whenever I hear something on TV or the radio about diabetes my ears perk up and I listen carefully. This past week there were a few things that caught my attention. First I heard...


Tool for Your Practice: AADE Super Bowl Game Day Tips for People with Diabetes

Despite what many think, diabetes does not have to deter people who have the disease from enjoying Super Bowl Sunday parties along with everyone else, according to the American Association of Diabetes Educators (AADE). In fact, managing your...


Editor's Note: Diabetes and Cardiovascular Disease, Lifestyle Habit Changes, and More....

Every week there is a new study coming out showing the relationship between diabetes and cardiovascular disease. There are over 1.1 million Americans who will have a serious heart attack in 2011 and there are over 80 million who have one or more...


Tool for Your Practice: Challenges and Opportunities to Control Diabetes

Challenges and Opportunities to Control Diabetes This new report,...


The Use of Farnesoid X Receptor (FXR) Agonists and 11 Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitors in Diabetes Management

By Iriny Nashed, PharmD Candidate Just when we thought we had it all figured out when it comes to diabetes management, we find there are not only new drugs on the horizon but new classes of medications that might just change the...


Case Study: Lilly Jaffe

Lilly Jaffe, of Chicago, was diagnosed with type 1 diabetes more than ten years ago, at the tender age of one month. What has happened to Lilly over the past few years is remarkable....


Ratio Of Good To Bad Bacteria In Stool Samples Of Children As Young As Four Months Could Predict Those Who Will Develop Type 1 Diabetes

Dr. Mark Atkinson, Ph. D., American Diabetes Association Eminent Scholar The University of Florida


Hyperglycemic Emergencies

Lana Kravarusic Doctor of Pharmacy Candidate, University of Florida 


How to Easily Reap the Health Benefits of Physical Activity

By


America's Silent Killer: Oprah and Dr. Oz Want to Save Your Life

By...


Being Female and Athletic: Special Concerns for Diabetic Women Only

If your patients are female, past puberty, and still young enough to be menstruating, then you’ll want to read what Sheri Colberg, Ph.D., FACSM, has to say in this week’s feature; Being Female and Athletic: Special Concerns for Diabetic...


New Perspectives In Oral Care For Those With Type 1 And Type 2 Diabetes

Charles W. Martin, DDS, founded DentistryForDiabetics, a nationwide group of dentists committed to helping those with diabetes. He authored the book Don’t Sugarcoat it: The Story of Diabetes and Dentistry and we are happy that he has joined...


Helping Parents Stay on Their Teen's Diabetes Team

Most times when we talk about teenagers and diabetes we are talking about type 1 patients, but with the large increase in adolescent cases of type 2 diabetes, all practitioners are likely to see these patients. Since there is not as much urgency...


Your First Year with Diabetes: What to Do, Month by Month

For the past 5 years Theresa Garnero, APRN, BC-ADM, MSN, CDE, has brought us some great laughs with her diabetes cartoons. But all those letters after her last name also means she knows something about diabetes care. She has just completed the book...


Preteens, teens doubled use of diabetes drugs

A recent article in Pediatrics, discussed how preteens and teens have doubled use of diabetes drugs in the past 4 years and that the prevalence is dramatically higher among young girls vs. boys. Why is this occurring? Why is it higher in girls?...


Presentations

Incretins, Part 1 of 7

This first of seven sets of Homerun Slides begins with GLP-1 physiology, then examines ...


Glycemic Disorders Part 1

The slides in this section provide an overview of the...


Screening for Diabetes and Pre-Diabetes

Patients who...


 
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