AACE: Empagliflozin: Another SGLT2-I on the Rise
Empagliflozin shows improvements in key diabetes parameters as well as weight reduction....
Hormone from Fat May Play Key Role in the Treatment of Type 2 Diabetes
Elevated levels of a hormone released from adipose tissue may be the key link in the development of type 2 diabetes in obese patients....
Cells That Increase Fat Burning Found in Humans
The find is crucial for fat research and future treatment of obesity....
Intermittent Fasting May Improve Diabetes and Reduce Cardiovascular Risk
Fasting diets may help those with diabetes and cardiovascular disease, alongside established weight loss claims....
Being Obese in Your 20's Increases Risk of Heart Disease at 55
Danish study found overweight males in their 20s had worse health in middle age....
Being Overweight and Drinking Increases Risk for Liver Damage
Women are at even higher risk for chronic liver disease....
No Link between Diabetes Remission, Weight Regain after Gastric Bypass
Weight regain among diabetic patients who have undergone gastric bypass is not associated with remission of diabetes....
Women with Gestational Diabetes may Experience Excessive Fetal Growth
Researchers looking at over 100,000 pregnancies find that gestational diabetes is one of the greatest risks for delivering a large-for-gestational age baby....
Apple-Shape May Increase Risk for Kidney Dysfunction
"Apple-shaped persons -- even if totally healthy and with a normal blood pressure -- have an elevated blood pressure in their kidneys."...
Resveratrol Shows No Metabolic Effect in Obese Men
Study shows data that negates resveratrol's use in metabolic disorders as a nutritional supplement....
Diet Versus Gastric Bypass for Diabetes Patients
Reduced calories before and after surgery improves diabetes in type 2 patients but not the actual surgery....
Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #30: Macrovascular Complications, Part 2
Richard S. Beaser, MD
Michael Johnstone, MD
Lifestyle Intervention for Prediabetes Is Successful
A community-based diabetes-prevention program produced significant reductions in blood glucose and body mass index (BMI) among individuals with prediabetes, while also reducing costs at 2 years....
High Carbohydrate Consumption During Infancy Has Long-standing Effects
In an animal study, high-carbohydrate intake after birth led to detrimental long-term effects….
Comparing Calories to Miles Makes Impact
Choosing foods according to the distance needed to burn makes a difference....
Gastric Banding Works Long Term
Gastric banding shows improvements in cardiovascular risk, lipids and glucose and the benefits persisting at 5 years and continuing....
Breastfeeding May Not Reduce Risk of Later Obesity in Children
Recent study finds breastfeeding does not lower risk of obesity....
Calories Trending Downwards As Obesity Is Going Upwards?
Americans eating less and getting fatter….
Study Explains Weight Gain with Diabetes Therapy
Weight gain from intensive glucose-lowering treatment is more likely in patients….
Surgery May Not Be the Most Cost-Effective Option
Weight loss surgery does not lower health costs over the long run….
Early Death Predicted with Cardio Risk Factors
Adolescents and young adults with a range of cardiometabolic risk factors have an increased risk of dying before they turn 55….
Diabulimia: the Diabetic Eating Disorder
Diabetic patients are more than twice as likely to have an eating disorder….
Losing Weight with a Fat Transplant
A new treatment that could help patients shed the excess weight….
Old Asthma Drug Causes Weight Loss
Old asthma drug could potentially reverse diabetes….
Qsymia Weight-loss Drug Improves Cardiovascular Risk Profile
The dose-related weight loss was also accompanied by improvements in cardiovascular disease risk factors....
Obesity Leads to Vitamin D Deficiency
While previous studies have linked vitamin D deficiency with obesity….
New England Journal Refutes Weight-Loss Beliefs in New Review
With data from the scientific literature, some of the most firmly held beliefs about weight loss are unproven or downright untrue....
Mechanism that Links Diabetes and Obesity with Cancer Discovered
Sustained high levels of sugars damage our cells and can….
Parents of Baby Boomers Healthier than Their Kids
Today's baby boomers do not fare very well compared with….
GLP-1 Agonists May Be Effective for Obese Adolescents
Preliminary evidence from a clinical trial suggests that treatment with GLP-1 receptor agonists was associated with….
Low Adiponectin in First Trimester Linked to GDM
Also linked to insulin resistance regardless of adiposity or glycemic measurement....
Reducing Risk of Diabetes in Pregnancy with a Supplement
A nutritional supplement may help protect women at risk for gestational diabetes....
Office Wellness Programs Work
Sixty-two percent of workers believe workplace wellness programs are successful in improving health and reducing health risks....
New First-ever Guidelines for Type 2 Kids
Step One – Start on insulin, according to the American Academy of Pediatrics which has issued guidelines for the management of type 2 diabetes in children and teenagers aged 10 to 18....
FDA Approves Nesina, Kazano and Oseni Oral Medications to Treat Diabetes
A new DPP-4 inhibitor is approved along with some combinations....
Exercising on Empty Stomach Burns 20% More Fat
A new study has found that exercising on an empty stomach in the morning can….
Type 2's Need to Keep Kidneys Healthy
One in every 10 Americans has diabetes, and over a third of those will….
Women Have to Do 20% More than Men
Women have to do about 20% more exercise to get the same benefits….
The Best Predictors of Heart Disease Death Risk
Combining two measurements to predict heart disease death risk is better than any one measurement....
Which Is More Important: Blood Sugar, Blood Pressure or Cholesterol Targets?
For people with diabetes, meeting the recommended guidelines for blood pressure and cholesterol is….
Meal Times Can Affect Weight Loss Success
Eating earlier rather than later can….
Metabolic Syndrome in 40's Linked to Exercise at Age 16
Television viewing habits and leisure-time physical activity at the age of 16 years independently predicts….
Lap-Bands Can Be Effective for Long-Term Weight Loss
Have the current studies finally answered the question on the effectiveness and safety of one type of gastric surgery?...
Weight Loss Achieved by Two Lifestyle Interventions
Two different lifestyle interventions modeled after those delivered in the Diabetes Prevention Program (DPP) produced significant weight loss among overweight or obese adults in a primary care setting....
High Insulin Levels Could Result in Obesity
Study sheds new light on the link between high insulin levels and weight gain....
Simple Formula Calculator Predicts Child Obesity Risk at Birth
A simple assessment can predict at birth a baby's likelihood of becoming obese during childhood....
Americans Adjusting Their Ideal Weight Upward
Americans increase what they think their ideal weight should be....
Psoriasis and Obesity Go Together in Children
Significantly more children with psoriasis present as overweight or obese compared with control patients without the inflammatory disease, according to a multicenter, cross-sectional, international study....
Medicare to Pay for Obesity Counseling in the Name of Prevention
A recent landmark decision by the Centers for Medicare and Medicaid Services (CMS) represents an important first step toward addressing one of the great ironies of American health care....
New Study Demonstrates Low-Carb Diets Reduce Risk for Heart Disease and Inflammation
When overweight or obese people lose weight, using a low carb diet, they can have a significant reduction in inflammation throughout their body, as measured by three common markers....
Benefits of Weight Loss in Diabetes Questioned
Obese people with diabetes who lost weight didn't lower their risk of having a heart attack or stroke....
High-protein Diets Work
Participants who were on a high-protein diet lost 1.8 extra pounds and more body fat at 12 weeks compared with those on a standard-protein diet....
Gaining Weight after Diabetes Diagnosis Increases Mortality
Adults who gained weight during the first year following their initial diagnosis with type 2 diabetes had a significantly increased risk for cardiovascular-disease death and for all-cause death....
Smoking during Pregnancy Tied to Obesity in Kids
But breast-feeding and late weaning may cut some of the child's risk....
Healthy Fat Patients Have Lower Risk of Mortality, CVD Morbidity
Obese individuals with high levels of cardiorespiratory fitness and a healthy cardiometabolic profile have a lower risk of mortality and cardiovascular events, including cardiovascular death, than individuals who are metabolically unhealthy...
Child Obesity Risks Greater than Thought
Children who are obese may have an even higher risk for heart disease, diabetes, and other weight-related diseases later in life than has been thought....
Whey Protein Helps to Fight Obesity and Type 2 Diabetes
Taking whey protein isolate or whey protein concentrates may help treat type 2 diabetes mellitus and prevent obesity....
Three More Studies Link Sugary Drinks and Weight Gain
Three new studies published in the U.S. reaffirm a link between sweet soda and fruit drinks to an epidemic of obesity....
Visceral Fat Not Obesity Increases Risk of Diabetes
Having excess visceral fat and insulin resistance -- but not being obese in and of itself -- appears to put heavier patients at risk for prediabetes and diabetes....
Children without Brothers or Sisters Have 50% Higher Risk of Obesity
Scientists have pinpointed a potential risk factor for overweight and obesity early in life and it has to do with how many siblings a child has....
Fat and Getting Fatter: U.S. Obesity Rates to Soar
According to an advocacy group, by 2030 more than half of the Americans in the vast majority of states, will be obese....
Childhood Obesity Affects Brain Development
Brain development issues may occur in children who are overweight, obese, or at risk for metabolic syndrome....
Why Some Obese May Not Develop Diabetes
A lone genetic mutation appears to simultaneously enhance insulin sensitivity while increasing the risk of obesity....
Love Handles Increase Risk of Death by 50% with Normal BMI
Where people store fat may ultimately determine their risk for developing diabetes and heart disease....
Heart Protection with Weight Loss
A small trial suggests a moderate weight loss induced by a hypocaloric diet (low calorie diet) may help protect cardiac function in obese women....
Using Antibiotics in Babies May Increase Risk for Obesity and Diabetes
New research suggests that giving babies antibiotics between the ages of 10 months and 3 years may increase their chances of being overweight in childhood....
The Obesity Paradox in Diabetes
Normal-weight adults with newly diagnosed type 2 diabetes had a significantly greater mortality risk than their overweight counterparts, a pooled analysis of five large cohort studies showed....
Americans Underestimate Weight Gain
Even though the average adult weight rose in 2008-2009, most surveyed thought they'd dropped pounds....
'Beige' Fat the Key to Fighting Obesity, Burning Calories
A newly discovered kind of fat in adult humans could help reduce the risk of obesity....
Heavy Kids Have Heavy CV Risk Factors
Two-thirds of severely obese children already have at least one heart disease risk factor as early as age 2....
Besides Diabetes and CVD, Obese Children Will Have 50% Higher Risk of Colon Cancer
The newest reason for doing everything possible to reduce childhood obesity names certain cancers as risks associated with a high BMI....
Liraglutide Shows Decreased BMI and Waist Circumference
New data is showing a decrease in waist circumference in patients with type 2 diabetes treated with liraglutide and correlates with positive alterations in inflammatory markers....
Waist Size Determines Cardio-Metabolic Risk in Diabetes
A bigger waistline, coinciding with a higher risk of cardio-metabolic complications in type 2 diabetes patients, suggests that waist measurement is critical for this population....
FDA Approves Phentermine-Topiramate Combo for Weight Loss
The FDA has approved the weight-loss drug Qsymia, formerly Qnexa, which now joins lorcaserin (Belviq), as the first anti-obesity medications to enter the US market since 1999....
First Anti-obesity Vaccine Shows Promise
A vaccine has been developed that could reset the body's metabolism and prompt weight loss even with a modest change in calories taken in or burned up in exercise....
Obesity Does Not Increase Mortality Risk
It is assumed that obese people are at a higher risk of mortality but a new study has found that obesity does not increase mortality risk....
New Research Shows Americans Are Informed Yet Not Self-Aware
Eight-two percent of Americans are aware that being overweight is a key risk factor for diabetes, yet those at risk are not applying this logic to themselves....
FDA Approves Lorcaserin (Belviq) for Treatment of Obesity
First weight loss drug to be approved by the FDA in thirteen years....
Weight Loss Aided in Diabetic Patients by Experimental Drug
An experimental drug helped significantly more overweight patients with diabetes shed pounds, compared with placebo....
Obesity Surgery Can Boost Risk for Alcohol Abuse
According to a large study to demonstrate a potential link, the most common type of obesity surgery may increase patients' chances for alcohol abuse....
UCTV Prime: The Skinny on Obesity (video)
Is sugar a toxin that's fueling the global obesity epidemic? That's the argument UCSF's Dr. Robert Lustig made ...
Simply Suppressing Hedonism or Truly a Magic Bullet for Obesity?
Aaron I. Vinik, MD, PhD, FCP, MACP
Eastern Virginia...
Letter from the Editor #615: Qnexa FDA Advisory Panel Approval
When it comes to weight loss medications the FDA's motto appears to be, "If at first you don't get approval, try, try, again," and it worked as an FDA advisory panel recommended the approval of Qnexa after two previous rejections (
Successful weight loss with GLP-1 agonists
Summary Insights
GLP-1 agonists are effective in weight loss as they delay gastric emptying, induce satiety, and decrease food
These agents have been successfully studied in obese,...
Letter from the Editor #607
Welcome back from the holiday season. This past week has been a real workout. Everyone who put health on the back burner last month seems to be showing up in our offices, wanting immediate service and quick fixes. In addition the "Resolution"...
United States of Diabetes Report
You can use the information in this report to provide evidence for your ...
Weight-Loss Surgery and the New Addiction, Part 2 of 2
By Tricia Greaves, President of The Nelson Center
Obese Children with Disabilities Tool Kit
Children with special needs are far more likely to be overweight or obese than their counterparts according to a new report, "Finding Balance: Obesity and Children with Special Needs." This landmark report, the first to focus exclusively on...
Managing Clinical Problems in Diabetes, Case Study #7: Mrs. RS
Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath
One Reason Patients Don't Follow Doctors' Orders: The Emotional Barriers to Weight Loss
by Tricia Greaves, President,...
Letter from the Editor: Summer Temptations, Emotional Barriers to Weight Loss and More
Now that we are past Memorial Day, school is almost done, and the outdoor season is officially upon us, it is interesting to watch how patients look for excuses to not care for their diabetes. End-of-school...
Editor's Note: Emotional Barriers to Weight Loss and Mrs. KB
This week's Case Study deals with the misconceptions that we often make about how people listen to what we are saying and how we think we told them something that we really didn't. This is especially true when we are trying to get them...
Letter from the Editor: History of Insulin Therapy and New Diabetes Treatment Possibilities
Last week I was discussing insulin therapy with my interns as we were evaluating insulin choices for a local physician. The consensus was to start on a long acting insulin like glargine and then titrate based on glucose levels with a patient...
Unexplained Weight Loss and Decreased Insulin Needs in Severely Obese Type 2 Patients
by Ashley Berry, Mercer University Doctor of Pharmacy Candidate 2011
Is it possible for an obese Type 2 diabetic patient who administers large quantities of insulin daily to b...
Letter from the Editor: Unexplained Weight Loss
Over the past couple of months I have received calls from three of my old insulin pump patients asking me to decrease their doses. These patients were all using over 400 units of insulin a day and were at least 100 pounds...
Diabetes Disaster Averted #23: Medication Confusion
A middle-aged woman, mildly obese, with Type 2 diabetes was hospitalized in the ICU, and the order on her chart was documented "Lispro 90 units at HS," then the "9" was crossed off and a "6" written above it....
Letter from the Editor: New Reports, Starbuck's Trenta and the Need for More Clinicians
New reports over the past couple of weeks tell a lot about our health. First it was 1 in 3 Americans have either prediabetes or diabetes and then we got news that over 50% of us are either obese or overweight. Last ...
Why the Whole World Is Going to Develop Diabetes Sooner or Later
By
Are Exercise-Induced Low Blood Sugars Making You Fat?
Letter from the Editor: Technology, Human Interaction and Exercise Weight Gain
This weekend Steve and I are at the International CES Show in Las Vegas, and technology for health is booming. Two years ago, not a single health related exhibit was available, last year there were 2 and now there is a whole section of the show...
Diabetes Disaster Averted #11: Label Literacy
I am a dietitian working as a diabetes educator. I often work with patients on insulin, and teach insulin to carb ratios and correction factors....
Letter from the Editor: Lap-Band at Birth -- Is It Possible?
I was reviewing some charts with a physician this past week and she made a comment about how many of her younger patients, 18-30 year olds, were overweight and just keep getting bigger. Jokingly I commented that maybe we should put a Lap-Band on at...
Editor's Note: Balancing Weight Loss and Glucose Control
Weight loss and glucose control-- the Holy Grail of diabetes care. We see it over and over again. Obesity often leads to diabetes and then the battle begins: get the weight down, keep the A1c down, be more aggressive managing both and reduce the...
Jumpstart Your Metabolism: How to Lose Weight by Changing the Way You Breathe
By Pam Grout
Reviewed by Sanaz Derakhshan, PharmD Candidate, LECOM Bradenton
Managing Type 2 Diabetes: Balancing HbA1c and Body Weight
Annie A. Mavian, DO; Stephan Miller, PhD; and Robert R. Henry, MD
Abstract: Most patients with type 2 diabetes present with comorbid overweight or obesity. Reaching and maintaining acceptable glycemic control is more difficult in...
Letter from the Editor: Further Setbacks for Weight Loss Drugs
We all know that insulin dosing mistakes are the number one medical error, but what happens when our patients don’t take enough insulin? They often develop DKA or HHS. How often do these occur, why do they occur, what is the difference...
New Weight Loss Combination Ready for FDA Approval
by Isaak Smith, PharmD Candidate, University of Florida College of Pharmacy
Contrave (naltrexone SR/bupropion SR) is an investigational product from Orexigen, a company that specializes in the treatment of...
Genetic Weight Loss Control: Creating the Perfect Program for Your Patients
Catalina Pulecio
Doctor of Pharmacy Candidate, College of Pharmacy, Western University of Health Sciences, Pomona, California
Nutrigenomics is a fast-moving field of research that combines...
Sarcopenic Obesity: Just One of the Many Potential Perils of Weight Loss without Exercise
By
YOU: On A Diet, Revised Edition: The Owner's Manual for Waist Management
By Dr. Michael F. Roizen and Dr. Mehmet C. Oz
Get Your Kids Moving, Too
The Serotonin Power Diet
by Judith Wurtman, PhD, and Nina Frusztajer, MD
HIV-infected patients are at an increased risk for developing Diabetes
More and more patients with HIV are controlling their disease well. When viral loads are under control, patients often are seen by clinicians for other problems. Diabetes seems to be one of those problems that get a lot of attention. My current...
Preteens, teens doubled use of diabetes drugs
A recent article in Pediatrics, discussed how preteens and teens have doubled use of diabetes drugs in the past 4 years and that the prevalence is dramatically higher among young girls vs. boys. Why is this occurring? Why is it higher in girls?...
How the Liver Affects Insulin and Vice Versa: Part 2, Obesity and Lipid Metabolism
Andre McMahon, PharmD Candidate, University of Florida College of Pharmacy
Dave Joffe, Editor-in-chief, Diabetes In...
Diabetes Mellitus 101 for Medical Professionals, Part 3 of 9
In this week's set of Homerun Slides, we discuss whether it is possible to delay the...
Pathophysiology in the Treatment of Type 2 Diabetes: Newer Agents, Part 1 of 5
This week we begin a new five-part Homerun Slides series on Pathophysiology in the...
Obesity and Socioeconomic Status in Adults
Of the approximately 72 and a half million adults who are obese, 41% (about 30 million) have...
Insulin Resistance, Part 2 of 3: Inflammation Markers
Plasminogen is an acute phase protein and precursor to plasmin, which...
