The Relationship Between Diabetes and Cancer

Jan 28, 2020

Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Antonio Bess, Pharm D Candidate, Florida Agricultural & Mechanical University School of Pharmacy

Diabetes is a risk factor for specific cancers, yet cancer screenings are performed less on people with diabetes than people without diabetes.

The link between cancer and diabetes is not entirely understood, but biological mechanisms linking diabetes and cancer are hyperglycemia, hyperinsulinemia, increased bioactivity of insulin-like growth factor 1, oxidative stress, dysregulations of sex hormones, and chronic inflammation. Although there is a known risk for cancer for people with diabetes, routine checks are still absent, and the potential of early detection and treatment of cancer is missed....

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