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The Link Between Obesity and Incidence Of Dementia

Sep 12, 2020
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Fairuz Afram, PharmD Candidate, University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences

Higher incidence of dementia tied to central obesity in English women.  

Dementia is attributed to numerous risk factors, with age being the strongest. Approximately 85% of dementia cases occur in individuals 75 years and older. Besides age, there are multiple modifiable risk factors associated with dementia; obesity is one of those risk factors. Overweight and obesity have become a public health priority worldwide due to the numerous health risks linked to them. Excess body fat is associated with the accumulation of brain lesions, changes in energy metabolism, and brain volume deficits, an early marker of neurodegeneration. However, the link between high body mass index (BMI) and dementia has never been clear....


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