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Targeting Postprandial Glucose as it Relates to A1C and Cardiovascular Disease

Nov 21, 2020
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Tarshay Boyd, PharmD. Candidate, LECOM School of Pharmacy

Blood glucose readings, A1c levels, fasting blood glucose, and postprandial glucose (PPG) all have one similarity factor: to control and manage glycemic control in both type 1 and type 2 diabetes.  These measurements are key monitoring parameters that medical providers assess for each patient.  A1c levels have now been linked to the postprandial glucose levels as they correlate to the risk of cardiovascular disease.  In a recent study on the importance of postprandial glucose related to A1c and cardiovascular disease, the authors sought to describe PPG's significance for the overall A1C levels.  This study provided results from multiple studies showing the cardiovascular benefit of PPG reduction and how different therapeutic agents can manage PPG in individuals with type 2 diabetes.    

In an online interview, Q&A with Dan Pollom, MD, Senior Medical Advisor, Eli Lilly, and Company, the question was asked:  Why is postprandial glucose a risk factor for cardiovascular disease? What are the benefits of postprandial glucose as it relates to A1C and cardiovascular disease?

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